Teen brain study: can hormone pills calm suicide risk?

NCT ID NCT07544966

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how natural hormone changes during the menstrual cycle may make some teenage girls more irritable or depressed, especially those at risk for suicide. Researchers will give 50 girls ages 12-16 either a birth control pill to keep hormones steady or a placebo for 8 weeks each, then compare mood and brain scans. The goal is to understand the brain connections involved, not to test a new treatment.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Biomedical Research Imaging Center (BRIC) at UNC

    Chapel Hill, North Carolina, 27517, United States

  • Carolina Crossing

    Chapel Hill, North Carolina, 27517, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••