Can a Once-Daily pill tame ADHD and emotional storms?
NCT ID NCT07759154
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This trial is testing whether an experimental medication called centanafadine, taken once daily as extended-release capsules, can help adults with attention-deficit/hyperactivity disorder (ADHD) who also experience emotional dysregulation—difficulty managing emotions like irritability or mood swings. About 80 adults with a confirmed ADHD diagnosis and significant emotional symptoms will receive the drug for 8 weeks. Researchers will measure changes in ADHD symptoms and emotional control using standardized rating scales to see if the treatment offers meaningful improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- centanafadine extended-release capsules
- What this could lead to
- If successful, this could offer a new daily medication option for adults with ADHD who also struggle with emotional control, potentially improving both focus and mood stability.
- What could go wrong
- This is an early-phase, open-label study without a placebo group, so results may be influenced by expectations. The drug may not prove more effective than existing treatments, and side effects are still being evaluated.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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