Otsuka Pharmaceutical Development & Commercialization, Inc.

This study is testing if a once-daily capsule called centanafadine can help control symptoms in adults who have both Attention-Deficit/Hyperactivity Disorder (ADHD) and anxiety. Over 300 participants will take either the drug or a placebo for 8 weeks to see which is more effectiv…

This study is testing a new oral medication called JNT-517 to see if it can safely and effectively lower blood phenylalanine (Phe) levels in adults with PKU. About 120 participants will take either the study drug or a placebo (a pill with no medicine) for the first six weeks, fol…

This is a first-in-human study to check if a new injectable drug called VIS171 is safe for people with certain autoimmune diseases like lupus, alopecia areata, or a kidney disease called FSGS. About 30 participants will receive the drug along with their standard care for up to a …

This study is testing whether adding a new drug called quabodepistat to existing tuberculosis medications can shorten treatment for drug-resistant TB. Researchers want to see if a 4-month treatment works as well as the current 6-month standard, while also being safer. The trial w…

This study is testing whether a new medication called SEP-363856 (Ulotaront) can reduce symptoms in people experiencing an acute schizophrenia episode. Researchers will compare the drug against a placebo in 522 hospitalized participants over 6 weeks. The main goal is to see if th…

This study is testing a medicine called tolvaptan in infants and children with a rare, serious genetic kidney disease (ARPKD). The main goal is to see if the drug is safe for young patients and if it can help slow down the worsening of their kidney function over 18 months. The tr…

This early-stage study aims to understand how a new ADHD medication called centanafadine works when taken with common stimulants like methylphenidate (Ritalin) and lisdexamfetamine (Vyvanse). It will involve 42 healthy adults to check for safety issues, focusing on changes in hea…

This early-stage study aims to understand how an experimental medication called MSP-2020 attaches to specific targets in the brain. Researchers will use brain scans and blood tests in 18 healthy male volunteers to measure how the drug interacts with brain receptors and how long i…