New pill aims to quench rare kidney Disorder's thirst for water

NCT ID NCT07525960

First seen Apr 20, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This early-stage trial tests a daily capsule called NDI-5001 in 24 adult men with a rare inherited kidney disease that makes them produce huge amounts of urine and feel constantly thirsty. The main goal is to check the drug's safety and how it affects urine volume and concentration. Participants must have a specific genetic mutation and low urine concentration at the start.

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