Could a simple estrogen pill reveal hidden oxytocin deficiency?
NCT ID NCT07361263
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This study is testing whether taking estrogen pills (estradiol valerate or ethinylestradiol) can safely trigger the release of oxytocin, a hormone important for social bonding and childbirth. Researchers will measure oxytocin levels in 28 healthy volunteers and patients with AVP deficiency (a condition affecting water balance). The goal is to develop a new diagnostic test for oxytocin deficiency, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- estradiol valerate and ethinylestradiol (estrogen pills)
- What this could lead to
- If successful, this could lead to a safe, simple diagnostic test for oxytocin deficiency, helping doctors identify and manage this condition more accurately.
- What could go wrong
- This is a very early, small study (28 participants) focused on measuring hormone levels, not treating disease. The approach may not reliably stimulate oxytocin or may cause side effects from estrogen.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital Basel
RECRUITINGBasel, 4031, Switzerland
More trials for these conditions
Other studies related to the condition(s) this trial covers.