Could a simple estrogen pill reveal hidden oxytocin deficiency?
NCT ID NCT07361263
First seen Feb 01, 2026 · Last updated Jun 19, 2026 · Updated 20 times
Summary
This study is testing whether taking estrogen pills (estradiol valerate or ethinylestradiol) can safely trigger the release of oxytocin, a hormone important for social bonding and childbirth. Researchers will measure oxytocin levels in 28 healthy volunteers and patients with AVP deficiency (a condition affecting water balance). The goal is to develop a new diagnostic test for oxytocin deficiency, not to treat any disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Hospital Basel
RECRUITINGBasel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
estradiol valerate and ethinylestradiol (estrogen pills)
What this could lead to
If successful, this could lead to a safe, simple diagnostic test for oxytocin deficiency, helping doctors identify and manage this condition more accurately.
What could go wrong
This is a very early, small study (28 participants) focused on measuring hormone levels, not treating disease. The approach may not reliably stimulate oxytocin or may cause side effects from estrogen.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.