Scientists map the Brain's 'Stop' button for speech

NCT ID NCT07713706

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Lingyun Zhao Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study investigates how the brain suddenly stops speech that is already underway. Researchers will record brain activity from epilepsy patients who already have electrodes implanted for medical reasons, as they perform speech tasks. The goal is to identify the neural circuits involved in voluntarily halting speech, which could improve understanding of disorders like stuttering and aphasia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could reveal how the brain stops speech, potentially guiding therapies for stuttering and aphasia.
What could go wrong: This is a small, early-stage observational study with only 12 participants, so findings may not apply broadly. It does not test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

epilepsy Speech speech disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY SPEECH

Contacts and locations

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Locations

UPMC Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, 15224, United States

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