Can speech therapy slow language loss in progressive aphasia?

NCT ID NCT04881617

First seen Nov 14, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tests whether specialized speech and language therapy can help 60 adults with primary progressive aphasia (PPA) — a brain disease that slowly destroys the ability to speak and understand language. Participants receive therapy targeting word retrieval and speech production, and are followed for one year to see if communication improves or declines more slowly compared to untreated patients. The goal is to find effective treatments for a condition that currently has no medication.

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Contacts and locations

Locations

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • University of Texas

    Austin, Texas, 78712, United States

Conditions

Explore the condition pages connected to this study.