Can speech therapy slow language loss in progressive aphasia?
NCT ID NCT04881617
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two types of speech therapy for people with primary progressive aphasia, a brain disorder that slowly destroys language skills. Sixty participants will work on word retrieval or script practice with a clinician and at home. Researchers will measure changes in communication and use brain scans to see who benefits most.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lexical Retrieval Training and Video-Implemented Script Training for Aphasia (behavioral therapy)
What this could lead to
If it works, this could provide evidence-based speech therapy methods to help people with primary progressive aphasia communicate better for longer.
What could go wrong
This is a small, early-stage study with only 60 participants, and the disease is progressive, so any improvements may be temporary or not work for everyone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of California San Francisco
San Francisco, California, 94158, United States
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University of Texas
Austin, Texas, 78712, United States