New drug SPN-810 tested for kids with ADHD and severe behavior issues

NCT ID NCT00626236

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested four different doses of SPN-810 (molindone) in 78 children aged 6 to 12 with ADHD and serious conduct problems. The main goal was to see if the drug is safe and tolerable. Researchers measured behavior changes using a special rating scale. The trial is complete, but results are not yet widely available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SPN-810 (molindone)

What this could lead to

If successful, this could point toward a new treatment option for children with ADHD who also have severe conduct problems.

What could go wrong

This was a small, early-phase trial (phase 2) with only 78 children. It focused on safety and tolerability, not on proving the drug works. The results may not apply to all children, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder conduct disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alliance Research Group

    Richmond, Virginia, 23229, United States

  • CNS Healthcare

    Orlando, Florida, 32806, United States

  • Capstone Clinical Research

    Libertyville, Illinois, 60048, United States

  • Clinical Neuroscience Solutions, Inc.

    Memphis, Tennessee, 38119, United States

  • Florida Clinical Research Center

    Bradenton, Florida, 32408, United States

  • IPS Research

    Oklahoma City, Oklahoma, 73103, United States

  • Northwest Clinical Trials

    Bellevue, Washington, 98004, United States

  • Sarkis Clinical Trials

    Gainesville, Florida, 32607, United States

  • The Psychopharm Research Cntr - LSU Dept of Psychiatry

    Shreveport, Louisiana, 71103, United States