SOLID TUMOR

This is an early-stage study to test the safety and find the right dose of a new investigational drug called IMGS-001. It is for adults with advanced solid tumors that have come back or stopped responding to standard treatments. The study will first test several doses for safety …

This study is testing an experimental immunotherapy drug called KN035 for people with advanced solid tumors that have specific genetic markers (dMMR or MSI-H). The trial is for patients whose cancer has continued to grow despite receiving standard treatments. Researchers want to …

This is the first human study of an experimental drug called BL-M17D1 for people with advanced breast cancer and other solid tumors. The main goals are to find the safest dose and see how the body processes the drug. Researchers will also look for early signs that the drug might …

This is a first-in-human study to test a new injectable drug called SHR-A1811(sc) in people with solid tumors. The main goals are to understand how the drug moves through the body, check its safety, and see if it shows any early signs of helping to control the cancer. The study w…

This early-stage study is testing whether a probiotic pill called R-5780 is safe and tolerable for people with advanced solid tumors who are already receiving a standard immunotherapy. The goal is to see if adding this probiotic can help control the cancer and improve quality of …

This is a first-in-human safety study testing a new two-part treatment for people with advanced HER2-positive solid tumors that have stopped responding to standard therapies. First, a specially designed virus is injected directly into one tumor to help alert the immune system. A …

This early-stage trial is testing JK06, a new antibody-based cancer drug, in patients with advanced solid tumors that cannot be surgically removed. Researchers will determine the safest and most effective dose while monitoring how patients respond to treatment. The study involves…

This study is testing the safety of a new two-drug combination (avutometinib and defactinib) for children and young adults (ages 3-30) whose solid tumors have come back or stopped responding to standard treatments. The main goal is to find the highest dose that is safe and causes…

This early-stage trial is testing the safety and initial effectiveness of a new oral drug, STC-15, when given alongside an existing immunotherapy called toripalimab. It will enroll about 188 adults with specific advanced cancers—including lung, melanoma, endometrial, and head/nec…

This is the first study in people to test a new cancer drug called PYX-201. Researchers want to find a safe and effective dose for adults with advanced solid tumors that have spread or returned after other treatments. The study will also look for early signs that the drug can shr…

This is the first human study of a new experimental drug called XB628, designed to help the immune system fight cancer. The trial will test different doses of the drug in 75 people with advanced solid tumors that have returned or spread after previous treatments. The main goals a…

This is an early-stage study testing a new drug called BL-M24D1 in patients with advanced non-small cell lung cancer and other solid tumors. The main goals are to find a safe dose, check how the body processes the drug, and look for early signs that it might help control the canc…

This early-stage study is testing a new drug called TRK-950 in people with advanced solid tumors that have not responded to standard treatments. The trial has three parts: testing TRK-950 alone, testing it combined with an existing immunotherapy (nivolumab), and specifically test…

This is an early-stage study testing a new drug called BL-B16D1 in people with advanced head and neck cancer or other solid tumors that have returned or spread. The main goals are to find a safe dose, see how the body processes the drug, and check for any early signs that it migh…

This early-stage study is testing a new drug called BL-M17D1 in adults with advanced gastrointestinal cancers and other solid tumors that have a specific marker called HER2. The main goal is to find the safest dose and see how the body processes the drug. Researchers will also ch…

This is the first study in people to test a new oral drug called SB-4826 for advanced solid tumors and non-Hodgkin lymphoma. The main goals are to find the highest safe dose and see how the body processes the drug. For lymphoma patients, the drug will also be tested in combinatio…

This early-stage trial is testing a new oral drug, AL8326, combined with an existing immunotherapy (toripalimab) for people with advanced solid tumors that have come back or spread. The main goals are to find the safest and most effective dose of the new combination and to see if…

This is a first-in-human study testing a new experimental drug called 177Lu-SN201 in adults with advanced solid tumors that have progressed despite standard treatments. The drug is a radioactive nanoparticle designed to accumulate in tumors. The main goals are to find a safe and …

This early-stage study is testing a new oral medication called GIM-531 for people with advanced solid tumors that have stopped responding to standard treatments. The research will evaluate the drug's safety and effectiveness when taken alone and when combined with an existing imm…

This early-stage study is testing a new drug called SHR-9839, given as an injection under the skin, in combination with other cancer therapies. It aims to find a safe and effective dose and see if it helps shrink tumors in adults with advanced solid cancers. The study will enroll…

This study is testing whether adding an immunotherapy drug called TSR-042 before standard chemoradiation and surgery works better for advanced solid tumors with specific genetic features. Researchers want to see if this combination helps eliminate cancer cells more effectively. T…

This study is testing an experimental oral medication called JYP0015 in adults with advanced cancers that have specific RAS mutations, including pancreatic, lung, and colorectal cancers. The trial aims to find a safe dose and see if the drug can shrink tumors in patients who have…

This early-stage study is testing a new oral medication called YH42946 for people with advanced solid tumors that have specific genetic changes (HER2 or EGFR mutations). The trial aims to find the safest dose and see if the drug can shrink tumors in 161 patients who have run out …

This early-stage study is testing a new oral medication called IPG1094 in patients with advanced solid tumors that have stopped responding to standard treatments. Researchers will first determine safe dosage levels and then expand to see if the drug shows anti-tumor activity agai…

This study is testing a new oral drug, S241656, alone and in combination with other cancer therapies. It aims to find a safe and effective dose for adults with advanced cancers, including lung, pancreatic, and colorectal cancers, that have specific genetic mutations like KRAS or …

This study is testing a new oral drug, HRS-4508, for people with advanced non-small cell lung cancer that has stopped responding to standard treatments. It aims to see if the drug can shrink tumors and control the cancer, while closely monitoring its safety. The trial will enroll…

This early-stage study is testing a new drug called ONO-7428 in people with advanced solid tumors that cannot be surgically removed or have returned after treatment. The main goal is to find the highest dose that patients can tolerate safely and understand how the drug behaves in…

This study is testing a new combination of two experimental drugs, LB1410 and LB4330, for people with advanced solid tumors that have spread or cannot be treated with standard therapies. The main goals are to find a safe and effective dose and to see if the combination can shrink…

This study is observing how well umbilical cord blood stem cells from unrelated donors work for patients with serious blood cancers and disorders. Researchers will track how quickly patients' blood counts recover, how often the transplant fails, and the rates of disease relapse a…

This is the first study in humans testing a new drug called IBI3026 for people with advanced solid tumors that cannot be removed by surgery. The main goals are to find a safe dose and see how the body handles the drug. Researchers will enroll about 300 participants to carefully m…

This study is testing a new drug called BL-B01D1 for people with advanced solid tumors, including gynecological cancers that have returned or spread. The main goals are to find a safe and effective dose and to see if the drug can shrink tumors. It is for adults whose cancer has p…

This is the first human study of an experimental drug called OCT-598 for people with advanced solid tumors that have stopped responding to standard treatments. Researchers will test increasing doses to find the safest and most effective amount, both when given alone and when comb…

This early-stage trial is testing a new, personalized cancer vaccine. The vaccine is made from proteins extracted from a patient's own tumor tissue and mixed with an immune-boosting ingredient. The main goals are to see if the vaccine is safe to make and give, and to look for ear…

This study is testing whether an immunotherapy drug called ENVAFOLIMAB can help control advanced solid tumors that have stopped responding to standard treatments. About 126 patients with various advanced cancers will receive the drug as a simple injection under the skin every fou…

This study is testing an experimental drug called BL-B01D1 in patients with advanced solid tumors that have spread or can't be surgically removed. The trial aims to find the right dose and see if the drug can shrink tumors in people who have already tried standard treatments. Res…

This early-stage study is testing the safety and early effectiveness of an experimental cancer treatment called T3011. The treatment is injected directly into tumors and is being tested both alone and combined with an existing immunotherapy drug (pembrolizumab) in people with adv…

This is the first human study of an experimental oral medication called NP-101 for people with advanced solid tumors that have stopped responding to standard treatments. The main goal is to test the safety and determine the right dose for future studies. Researchers will also loo…

This is an early-stage study to find a safe dose for a new experimental drug called BGB-26808. It will be tested alone and in combination with an existing immunotherapy drug, tislelizumab, in adults with advanced solid tumors that have spread or cannot be removed by surgery. The …

This early-phase study is testing a new drug, CBP-1019, in combination with several other cancer therapies for people with advanced solid tumors that have spread. The main goals are to find safe dose levels and see if these combinations can help shrink tumors. The study is enroll…

This study is testing a new drug called SAR445877 for adults with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe dose and see if the drug, given alone or with other cancer treatments, can help shrink tumors. The trial is …

This early-stage study is testing a new combination of two oral drugs, BMS-986504 and olaparib, in adults with advanced solid tumors that have a specific genetic change called MTAP loss. The main goal is to find a safe and tolerable dose. Researchers will also check how the drugs…

This early-stage trial is testing a new drug called SB17170 in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the safest and most effective dose and to check for early signs that the drug might help shrink tumors.…

This is the first time a new drug called AT03-65 is being tested in people. The main goal is to find a safe dose for adults with advanced solid tumors that have stopped responding to standard treatments. Researchers will give the drug by IV and carefully monitor patients for side…

This study is testing a new cell therapy for people with solid tumors that have come back or haven't responded to standard treatments. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to recognize and attack cancer cells, and then infuse them …

This is the first study in people testing an experimental drug called CUSP06. It aims to see if the drug is safe and can help control advanced ovarian cancer and other solid tumors that have stopped responding to standard platinum-based chemotherapy. The study will enroll about 2…

This study is testing a new oral drug called TNG456, both alone and combined with another cancer drug (abemaciclib), in people with advanced solid tumors that have a specific genetic change called MTAP loss. The main goals are to find safe doses and see if the treatment can shrin…

This is an early-stage study to test the safety and initial effects of a new experimental drug called GNC-039 in adults with advanced solid tumors that have returned or spread after standard treatments. The main goals are to find a safe dose and see what side effects occur. Resea…

This early-stage trial is testing a new drug called SON-DP in people with advanced solid tumors that have not responded to standard treatments. The drug works by trying to reprogram cancer cells in the body, turning them back into normal tissue cells instead of killing them. The …

This is an early-stage study to test the safety and find the right dose of a new drug called SMP-3124LP for adults with advanced solid tumors that have progressed after standard treatments. The trial will also look for early signs that the drug can help control the cancer. It is …

This early-stage trial is testing the safety and early effectiveness of a new two-drug combination, OH2 and BS006, injected directly into tumors. It is for adults with advanced solid cancers who have already tried and stopped responding to standard treatments. The main goal is to…

This is the first human study of an experimental cancer drug called JBZ-001. Researchers are testing it in 25 adults with advanced solid tumors or blood cancers that haven't responded to standard treatments. The main goals are to find a safe dose and see how the body processes th…

This is the first study in people testing a new cancer drug called AGX101. It aims to find a safe and effective dose for patients with advanced solid tumors that have spread or cannot be removed by surgery, and who have no other standard treatment options left. The drug is given …

This early-stage study is testing a new experimental drug called HYP-6589 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe dose, see how the body processes the drug, and check for early signs that it might he…

This study is testing whether the drug selinexor can help control certain childhood solid tumors that have come back or have not responded to standard treatments. It is for children as young as 1 year old who have specific cancers like Wilms tumor, rhabdoid tumor, or MPNST, and w…

This early-stage study aims to find a safe and effective dose of a targeted radiation drug for children and teenagers with specific cancers that have come back or stopped responding to standard treatments. The therapy delivers radiation directly to cancer cells. Researchers will …

This study is testing a new drug called MORAb-202 in people with advanced ovarian, endometrial, lung, or triple-negative breast cancer. The main goals are to find a safe dose and see if the drug can shrink tumors. The drug is designed to target cancer cells specifically, and some…

This early-stage study is testing the safety and finding the right dose of a new drug combination (NEROFE plus doxorubicin) for people with advanced solid tumors that have specific genetic markers (KRAS mutation and ST2-positive). It will enroll 24 participants who have run out o…

This early-stage study is testing a new drug called SHR-7367 when given alongside other cancer medications. It aims to find a safe dose and see if the combination can shrink tumors in adults with advanced solid cancers. The trial will enroll about 100 participants to monitor side…

This is an early-stage study to test the safety and initial effects of a new experimental drug called GNC-077 in people with advanced breast cancer and other solid tumors. Researchers will give increasing doses to small groups of patients to find the highest safe amount. The main…

This is a very early study to test the safety and find the right dose of a new drug called BL-B01D1. It is for adults with advanced breast cancer or other solid tumors that have spread or cannot be removed by surgery and have few treatment options left. The main goals are to see …

This study is testing a new oral drug called IPN01194 in adults with advanced solid tumors that have spread and have specific genetic changes. The main goals are to find a safe and tolerable dose and to see if the drug can help shrink tumors. The study is open to people with cert…

This early-stage study is testing a new type of personalized cell therapy called GC203 TIL in adults with advanced solid tumors that have stopped responding to standard treatments. Doctors take a patient's own immune cells from a tumor, modify them in a lab to potentially fight c…

This study is testing whether adding the drug bevacizumab to standard chemotherapy helps shrink tumors more effectively before surgery in people with early or locally advanced HER2-negative breast cancer. The goal is to see if this combination leads to better outcomes, like compl…

This is the first human study of an experimental drug called PT0511 for people with advanced solid tumors that have specific KRAS genetic changes. The main goals are to find safe doses and see how the body processes the drug, both alone and combined with another cancer medication…

This is a first-in-human study to test the safety and early effectiveness of a new cell therapy called CLDN6 CAR-T, given with or without an RNA vaccine, for patients with advanced solid tumors that have come back or stopped responding to other treatments. The trial will enroll a…

This early-stage trial is testing a new drug called FOG-001 for people with advanced or spreading cancers that have specific genetic mutations. Researchers want to find the safest dose and see if the drug can shrink tumors or slow cancer growth. The study will include 575 partici…

This is the first study in people to test a new oral drug called NKT3964. It aims to see if the drug is safe and can help control advanced cancers that have spread and stopped responding to standard treatments. The study will enroll adults with specific advanced solid tumors, inc…

This study is testing whether taking two oral drugs, VS-6766 and defactinib, together can help control recurrent gynecologic cancers like ovarian and cervical cancer. It is for women whose cancer has a specific genetic change and has come back or worsened after at least one prior…

This is a first-in-human study to test the safety, side effects, and best dose of a new investigational drug called BB-1709. It is for adults with advanced solid tumors that have spread or cannot be removed by surgery and have stopped responding to standard treatments. The study …

This study is testing whether a 12-month course of oral medications can help keep cancer from coming back in children and young adults with high-risk solid tumors. After finishing standard treatment, participants take a combination of drugs (sirolimus, celecoxib, and low-dose che…

This is an early-stage safety study for a new drug called ANK-101, which is injected directly into tumors. It aims to find a safe dose for people with advanced solid cancers that have stopped responding to standard treatments. The study will test the drug alone in different types…

This is an early-stage study to find a safe dose of an experimental therapy called MQ710 for people with advanced solid tumors that have returned, spread, or stopped responding to standard treatments. The therapy is a modified virus designed to be injected directly into tumors. R…

This study is testing two new drug approaches for people with advanced bladder cancer and other solid tumors that have stopped responding to standard treatments. It will enroll 52 participants to see if either a single drug (SI-B003) or a combination of two drugs (BL-B01D1+SI-B00…

This early-stage trial is testing a new type of cell therapy for people with advanced solid tumors that have a specific protein called ALPP. The therapy involves collecting a patient's own immune cells, modifying them in a lab to better target the cancer, and then infusing them b…

This is an early-stage study testing the safety of a modified virus called VRT106, which is designed to infect and kill cancer cells. The virus is injected directly into tumors of patients with advanced solid cancers who have no other effective treatment options. Researchers will…

This is the first study in humans testing a new drug called BM230 for people with advanced solid tumors that have a specific marker called HER2. The main goal is to find a safe dose and see how the body handles the drug. It's for patients whose cancer has continued to grow despit…

This study is testing if adding an experimental drug called givastomig to standard immunotherapy and chemotherapy works better for controlling advanced stomach or esophageal cancer. About 180 adults whose cancer has spread and who have not yet received treatment for their advance…

This early-stage study is testing the safety of combining an oral drug called azeliragon with full brain and spine radiation in patients with aggressive cancer that has spread to the lining of the brain and spinal cord. The main goal is to find out if this combination is safe and…

This study continues to monitor patients who have already completed previous cancer treatment studies with dabrafenib and/or trametinib. It tracks 100 patients with various cancers including melanoma and lung cancer to understand the long-term safety of these medications. The goa…

This study is testing a new combination of two experimental drugs, 7MW3711 and JS207, for people with advanced solid tumors that have progressed after standard treatments. The main goals are to find the safest and most effective doses and to see if the combination can help contro…

This is the first human study of an experimental drug called PT0253 for people with advanced solid tumors that have a specific genetic change called KRAS G12D. The main goal is to find the safest dose and see how well the drug is tolerated in 115 participants. Researchers will al…

This early-stage study is testing a new drug called JZP815 in people with advanced or metastatic solid tumors that have specific genetic changes in the MAPK pathway. The main goals are to find a safe dose, understand how the drug works in the body, and look for early signs that i…

This early-stage study is testing the safety of a new combination treatment for patients with large, advanced solid tumors that have not responded to standard therapies. The treatment combines two types of targeted radiation with an immunotherapy drug (tislelizumab) that helps th…

This is a first-in-human study to test the safety and side effects of a new drug called BL-B16D1. It will involve adults with advanced breast cancer or other solid tumors that have spread and cannot be removed by surgery, and who have run out of standard treatment options. The ma…

This is the first time researchers are giving the experimental drug ASP5834 to people. The study aims to find a safe dose and check for side effects in adults with advanced solid tumors that have specific changes in a gene called KRAS. Some participants with colorectal cancer wil…

This is the first-ever study in humans of a new experimental drug called TH9619 for people with advanced solid tumors. The trial aims to find a safe and effective dose while checking how the body processes the drug and whether it shows signs of fighting cancer. It's open to adult…

This study is testing a new combination of an immunotherapy drug (atezolizumab) with three chemotherapy drugs for children and young adults whose solid tumors have returned or not responded to prior treatment. The main goals are to first check if the combination is safe and then …

This study is testing a new drug called HY0001a in people with advanced solid tumors that have not responded to standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors. It is for adults with cancers like esophageal cancer, lung cancer, an…

This early-stage study is testing the safety of a new experimental injection called Peptide Alarm Therapy (PAT) when given directly into tumors alongside standard immunotherapy. It's for adults with advanced solid tumors that have continued to grow despite one or more prior treat…

This study is testing a new drug called XL092, both by itself and in combination with other immunotherapy drugs, for people with advanced solid tumors that cannot be removed by surgery. The main goals are to find safe doses and see if the treatments can shrink tumors or slow thei…

This is a first-in-human study to test the safety and find the right dose of a new drug called TJ033721 (givastomig) for people with advanced or metastatic solid tumors. It will enroll about 330 patients whose cancer has progressed despite standard treatments or who have no other…

This is a first-in-human study to find a safe dose of a new drug, ASP3082, for people with advanced solid tumors that have a specific genetic change called KRAS G12D. The study will test ASP3082 alone and in combination with other cancer drugs in up to 681 participants. The main …

This is the first human study of an experimental antibody called GNC-077 for people with advanced non-small cell lung cancer and other solid tumors. The main goal is to find a safe dose and understand how the body processes the drug. Researchers will enroll about 20 participants …

This early-stage study is testing a new oral medication called INX-315 in people with advanced cancers that have spread or stopped responding to standard treatments. It aims to find a safe dose and see if the drug can help control cancers like certain types of breast and ovarian …

This is a first-in-human study to test the safety and determine the right dose of an experimental drug called BL-B16D1 in adults with advanced solid tumors that have spread or cannot be removed by surgery. The trial will enroll patients who have already tried standard treatments …

This study is testing a new drug called GDC-7035, both alone and combined with other cancer treatments, for people with advanced solid tumors that have a specific genetic change called KRAS G12D. The main goals are to find a safe dose and see how the body processes the drug. It w…

This is the first study in people of an experimental pill called MRTX1719. It is for adults with advanced solid tumors that have a specific missing gene called MTAP, which is found in some lung cancers, mesothelioma, and other cancers. The main goals are to find a safe dose, see …

This study is testing whether a new drug called BL-B01D1 works better when combined with an existing immunotherapy (PD-1 antibody) to control advanced cancers that have spread. It will involve about 570 adults with non-small cell lung cancer, nasopharyngeal cancer, or other solid…

This is an early-stage study to test the safety and find the right dose of a new oral drug called IDE397. It is for adults with advanced solid tumors that have a specific genetic change (MTAP deletion) and have stopped responding to standard treatments. The study will test IDE397…

This study is testing a new drug called TER-2013 in people with advanced solid tumors that have specific genetic changes. The main goals are to find a safe dose and see if the drug can shrink tumors. It is for patients who have run out of standard treatment options.

This is the first study in humans testing an experimental drug called BHV-1530 for adults with advanced or metastatic solid tumors that have stopped responding to standard treatments. The main goals are to find a safe dose, see how the body processes the drug, and check for early…

This is an early-stage study testing a new drug called BL-M24D1 in patients with advanced head and neck cancer or other solid tumors. The main goals are to find a safe dose, see how the drug moves through the body, and check for any early signs that it might help shrink tumors. R…

This study is testing whether using an Apple Watch and a special app can help monitor cancer patients during chemotherapy treatment. Researchers want to see if this remote monitoring system is easy for patients to use and if it can help detect potential health problems like fever…

This is the first-ever study in people of a new targeted cancer drug called BHV-1510. It aims to find a safe and effective dose for patients with advanced solid tumors that have stopped responding to standard treatments. The study will test the drug alone and combined with an exi…

This small pilot study is testing a new, highly personalized approach to treating advanced breast or stomach cancer. For each of the 10 participants, scientists will first use lab tests on their own tumor cells to find the best drug combination. Then, an artificial intelligence (…

This early-stage study is testing a new drug called NUC-7738 in adults with advanced cancers that have not responded to standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors, either by itself or combined with another immunotherapy drug.…

This study is testing a new drug called MCLA-129 in people with advanced cancers, including lung, head and neck, and colorectal cancer, that have progressed after standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors. The drug is design…

This is an early-stage study to find a safe dose and check the side effects of a new experimental drug called OBT076. The drug is designed to target and kill cancer cells that have a specific marker (CD205) and have stopped responding to standard treatments. The study will enroll…

This is a first-in-human, early-stage study to check the safety and find the right dose of an experimental drug called LB1410. The drug is designed to help the immune system fight cancer by blocking two different targets (PD-1 and TIM-3) at once. It will be given by IV to about 1…

This study is testing a new radioactive drug called 177Lu-FAP-2286 for people with advanced solid tumors that have stopped responding to other treatments. The drug is designed to find and deliver radiation directly to tumors by targeting a specific protein common in many cancers.…

This study is testing if a special dye called Indocyanine Green (ICG) is safe and useful for helping surgeons see and remove lymph nodes during cancer surgery in children. The dye is injected during the operation to make the lymph nodes that drain from the tumor easier to identif…

This study is testing a new type of imaging scan to see if it can better detect and monitor many different solid tumors. The scan uses a special tracer that attaches to a protein called Trop2, which is often found on cancer cells. Researchers will compare this new scan to standar…

This study is testing if a special dye called Indocyanine Green (ICG) can help surgeons better see and remove solid tumors in children and adolescents. During surgery, the dye is meant to make tumors glow under a special camera, potentially helping the surgeon find all the cancer…

This study is testing a new type of PET scan designed to detect a specific protein called CLDN18.2 on cancer cells. The goal is to see if this scan can accurately find tumors that have this protein, which could help doctors identify patients who might benefit from new targeted th…

This study is adapting and testing a program called CONVO for Latinx cancer patients. In the program, oncology nurses have a special conversation with patients about their personal values and goals for care. The goal is to see if these talks help improve communication and the ove…

This study is adapting a counseling approach called Meaning-Centered Psychotherapy to better serve Latino patients with advanced cancer. Researchers will work with about 285 participants to make the therapy culturally relevant and test if it improves spiritual well-being, reduces…

This study is testing a new program where nurses start conversations about palliative care early in a child's cancer treatment. It aims to see if these regular talks improve the child's quality of life, manage symptoms better, and reduce stress for family caregivers compared to s…

This study is testing whether a Spanish-language telehealth program called DESCANSO/REST is practical and helpful for Latino cancer patients struggling with depression, fatigue, and insomnia. Researchers want to see if patients complete the sessions and find them useful. The prog…

This study is testing whether a special pre-treatment program helps cancer patients feel better physically and emotionally. The program includes guided exercise and psychological support before patients undergo surgery or radiation. Researchers will compare 125 patients who recei…

This study is adapting a counseling program called Meaning Centered Psychotherapy to be more culturally relevant for Latino adults with advanced solid tumors. Researchers want to understand what affects quality of life for these patients and test if this adapted therapy can help …

This study aims to learn about the long-term side effects of CAR-T cell therapy in children and young adults with cancer. Researchers will follow 100 participants for up to two years to track how often they get serious infections, have slow blood count recovery, or experience las…

This study aims to learn more about rare cancers by collecting health information and biological samples from people who have them or are at risk. Researchers will follow 10,000 participants over time to understand how these rare tumors develop and behave. The goal is to use this…

This study aims to collect health and activity data from patients' smartphones to build a large research database. Researchers want to see if patterns in daily physical data can tell us something about cancer risk, diagnosis, or how patients respond to treatment. The study includ…

This study aims to understand how the body's immune cells respond to a new type of cancer vaccine. Researchers will collect blood samples from participants to examine how immune cells recognize and potentially fight cancer cells. The research will help scientists learn how these …

This early study aims to see how two new radioactive tracers travel through the body and gather in tumors. Researchers will give a single, tiny dose of one tracer to up to 32 patients with various solid tumors and then use PET/CT scans to track where it goes. The main goal is to …

This study aims to understand how common sleep problems are among adults who survived childhood cancer. Researchers will measure sleep patterns, fatigue, and thinking skills in 120 survivors using at-home sleep monitors and questionnaires. The goal is to identify connections betw…

This study is testing a new family communication tool called 'Let's Get REAL' to help children and teenagers be more involved in decisions about their stem cell or cellular therapy treatments. Researchers will work with 24 young patients (ages 8-17) and their parents to see if th…

This study is testing a new predictive tool to see if it can accurately forecast which patients with melanoma and other cancers will respond to immunotherapy drugs. It will involve 1,000 patients who are eligible for standard immunotherapy treatment. The goal is to see if this to…

This study is testing whether a simple blood test, called a liquid biopsy, can help doctors choose the best treatment for people with solid tumors. Researchers will check if the blood test can find genetic changes in the cancer and if using this information leads to better outcom…

This study aims to understand how cancer treatment affects a patient's ability to work and their overall well-being. It will follow 400 low-income men, many of whom are Latino, who are newly diagnosed with solid tumors. Researchers will track their work status, hours, financial s…

This study aims to analyze the genetic makeup of advanced cancers to find specific weaknesses that drugs can target. Researchers will test tumor samples from 10,000 adults with solid tumors or blood cancers. The goal is to use this detailed genetic information to match patients w…

This study aims to better understand and predict serious side effects that can occur when cancer patients receive immunotherapy drugs. Researchers will follow 940 adults with solid tumors who are starting a new immunotherapy treatment, collecting blood samples and health data ove…