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Can a simple test predict who will beat skin cancer with immunotherapy?

NCT ID NCT06536257

Recruiting now Knowledge-focused Sponsor: Melanoma Institute Australia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study is testing a new predictive model that analyzes tumor samples to forecast whether a patient with melanoma or other skin cancers will respond to immunotherapy. Researchers will compare the model's predictions with actual patient outcomes over six months. The goal is to see if this tool can help doctors personalize treatment decisions, potentially sparing non-responders from unnecessary side effects. The study plans to enroll 1,000 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors choose the right immunotherapy for each patient, avoiding ineffective treatments and their side effects.
What could go wrong
This is an observational study, not a treatment trial. The model may not be accurate enough to change practice, and results may not apply to all skin cancer types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

basal cell carcinoma cutaneous neuroendocrine carcinoma melanoma neoplasm skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BASAL CELL CARCINOMA CUTANEOUS SQUAMOUS CELL CARCINOMA MELANOMA MERKEL CELL CARCINOMA SOLID TUMOR

Contacts and locations

Locations

  • Chris O'Brien Lifehouse

    RECRUITING

    Sydney, New South Wales, 2050, Australia

  • Melanoma Institute Australia

    RECRUITING

    Sydney, New South Wales, 2065, Australia

  • Westmead Hospital

    RECRUITING

    Sydney, New South Wales, 2145, Australia

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