BASAL CELL CARCINOMA

This study is testing whether immunotherapy drugs, given alone or in combination, can help control advanced basal cell carcinoma that has spread or cannot be surgically removed. It will enroll about 57 adults with this type of skin cancer and assign them to different treatment gr…

This study is testing an experimental therapy called RP1 for people who have had an organ or bone marrow transplant and now have advanced skin cancer. RP1 is a modified cold sore virus that is injected directly into tumors to try to destroy them and boost the body's immune respon…

This study is testing whether giving one or two immunotherapy drugs before surgery can shrink advanced basal cell carcinomas on the head and neck. The goal is to see if shrinking the tumor first allows surgeons to perform a less extensive operation, potentially preserving importa…

This is an early-stage study to find a safe dose of an experimental therapy called MQ710 for people with advanced solid tumors that have returned, spread, or stopped responding to standard treatments. The therapy is a modified virus designed to be injected directly into tumors. R…

This study is for people with a difficult-to-treat form of skin cancer (locally advanced basal cell carcinoma) who have successfully cleared their tumor with special pills (Sonic Hedgehog inhibitors). Because the cancer often comes back after stopping the pills, researchers want …

This study is testing whether two different immunotherapy drug combinations can shrink high-risk basal cell skin cancers before surgery. About 30 patients will receive either a two-drug combo (Opdualag) or a single drug (Nivolumab) for a few months. The main goal is to see how we…

This study is testing a new tool that uses artificial intelligence (AI) to help surgeons during skin cancer removal. The AI analyzes special microscope images of the tissue in real-time, aiming to help the surgeon better distinguish between cancerous and healthy tissue. The goal …

This study is testing a new, non-invasive imaging device called LC-OCT. It is being used on patients with a common type of skin cancer (basal cell carcinoma) who are scheduled for a precise removal surgery called Mohs. The goal is to see if this scanner can help the surgeon bette…

This study is testing whether cancer patients prefer to receive their standard drug treatments at home instead of in a clinic. Researchers want to see if home-based care reduces the burden of travel and improves treatment satisfaction and quality of life for patients. A specializ…

This study is testing a new predictive tool to see if it can accurately forecast which patients with melanoma and other cancers will respond to immunotherapy drugs. It will involve 1,000 patients who are eligible for standard immunotherapy treatment. The goal is to see if this to…

This study aims to understand how a light-based treatment called photodynamic therapy (PDT) affects the body's immune response to basal cell carcinoma, a common type of skin cancer. Researchers will study 28 participants who are already scheduled for surgery to remove their skin …