Triple therapy aims to cure High-Risk skin cancer without disfigurement
NCT ID NCT07251413
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining an immunotherapy drug (cemiplimab), a topical cream (imiquimod), and laser therapy before surgery can cure high-risk basal cell skin cancer. About 18 adults with large or difficult-to-treat tumors will receive the combination or immunotherapy alone. The goal is to increase the chance of a definitive cure and reduce the need for disfiguring surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Clínic de Barcelona. Carrer de Villarroel, 170, L'Eixample
RECRUITINGBarcelona, Barcelona, 08036, Spain
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Hospital Miguel Servet de Zaragoza. P.º de Isabel la Católica, 1-3
RECRUITINGZaragoza, Zaragoza, 5009, Spain
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Hospital Ramón y Cajal. M-607, Km. 9, 100, Fuencarral-El Pardo,
RECRUITINGMadrid, Madrid, 28034, Spain
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Hospital Universitario Dexeus - Grupo Quirónsalud. Carrer de Sabino Arana, 19 Ed, Distrito de Les Corts
RECRUITINGBarcelona, Barcelona, 08028, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Botox before the knife: could a Pre-Surgery injection lead to Better-Looking scars?
- Could a lighter immunotherapy schedule keep advanced cancers in check?
- New skin patch could speed recovery after skin cancer removal
- AI reads skin lesions to predict cancer aggressiveness
- Needle-Free light therapy shows promise for common skin cancer
- Snap and measure: new photo method tracks nose shape after skin cancer surgery