Botox before the knife: could a Pre-Surgery injection lead to Better-Looking scars?
NCT ID NCT07720726
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This trial tests whether injecting Botox (abobotulinumtoxin-A) into the forehead muscles just before paramedian forehead flap surgery can improve the cosmetic appearance of the resulting scar. Adults with nasal skin cancer defects needing this reconstruction are randomly assigned to receive either Botox or a saline placebo injection before the procedure. Researchers will then compare scar appearance and patient satisfaction over time using standard scar scales and photographs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an injection of abobotulinumtoxin-A (Dysport, a type of Botox) into the forehead muscles before surgery
- What this could lead to
- If it works, this could offer a simple way to reduce scarring and improve satisfaction after forehead flap surgery for nasal skin cancer.
- What could go wrong
- This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. Botox injections carry risks like muscle weakness, headache, or injection site reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BASAL CELL CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a radioactive tracer reveal whether immunotherapy is working?
- Can a new nucleotide analogue boost cancer treatment?
- Can a new drug ST316 shrink Hard-to-Treat tumors?
- Can a single tracer light up cancer's first stop? a trial puts a hybrid dye-and-radioactive marker to the test.
- Could a lighter immunotherapy schedule keep advanced cancers in check?
- Immunotherapy before surgery may cut skin cancer recurrence