BASAL CELL CARCINOMA

This study tested the drug vismodegib in 55 people with advanced basal cell carcinoma (a type of skin cancer) to see if taking it before surgery could make the tumor smaller and allow for a less extensive operation. Participants took the drug for a period before their planned sur…

This early-phase study tested an experimental immunotherapy drug, cemiplimab, given as injections directly into skin tumors before surgery. The goal was to see if the drug is safe and how well it shrinks or eliminates the cancer. The study included 97 people with two common types…

This study followed 287 people with advanced skin cancer (squamous cell or basal cell) who were treated with cemiplimab in everyday medical practice. Researchers measured how well the drug shrank tumors, how long the effects lasted, and any side effects. The goal was to see if re…

This study tested whether taking a daily pill called sonidegib for 12 weeks could shrink basal cell skin cancers in cosmetically tricky areas (like the face) before surgery. The goal was to make surgery less scarring or even avoid it entirely. Sixteen adults with this type of ski…

This early study tested a new radioactive patch (CivaDerm) for treating common skin cancers like basal cell and squamous cell carcinoma. Ten adults with small tumors on their trunk or limbs received the patch to deliver targeted radiation to the skin surface. The main goal was to…

This study allowed people with certain cancers (ovarian, basal cell, or colorectal) who had already shown benefit from the drug vismodegib in an earlier study to keep receiving it. The main goal was to track side effects and see how many people had to stop treatment due to them. …

This study tested whether a special microscope (two-photon fluorescence microscopy) can accurately detect leftover basal cell carcinoma during Mohs surgery. Researchers compared its results to the standard frozen section method in 135 patients. The goal was to see if this new tec…

This study looked at the long-term safety of the drug Odomzo (sonidegib) in 323 adults with a type of advanced skin cancer called locally advanced basal cell carcinoma (laBCC) that cannot be treated with surgery or radiation. Researchers collected real-world data on side effects,…

This study looked at whether telling people about their genetic risk for melanoma (a serious skin cancer) changes how they protect themselves from the sun. Over 2,000 adults took part and reported their sun habits, like using sunscreen and avoiding burns. The goal was to see if p…