Drug shrinks skin cancer before surgery, may reduce cutting

NCT ID NCT02667574

Completed Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug vismodegib given before surgery to people with advanced basal cell carcinoma (a type of skin cancer). The goal was to see if the drug could shrink the tumor enough to allow for a smaller, less invasive surgery. 55 participants took the drug for a period before their planned operation. The study measured how much the required surgery changed compared to what was originally planned.

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Conditions

The condition(s) this trial relates to.

basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BASAL CELL CARCINOMA

Contacts and locations

Locations

CH de Boulogne sur mer

Boulogne-sur-Mer, Boulogne Sur Mer, 62321, France
CHU - Hôpital d'Estaing

Clermont-Ferrand, Clermont-Ferrand, 63003, France
CHU Ambroise Paré

Paris, Paris, 92104, France
CHU Bocage

Dijon, Dijon, 21079, France
CHU de Besançon

Besançon, Besançon, 25030, France
Centre hospitalier Lyon Sud

Pierre-Bénite, Pierre-benite, 69495, France
Clinique de Dermatologie

Lille, Lille, 59037, France
Hôpital Bichat

Paris, PARIS, 75018, France
Hôpital Haut-Lévêque

Pessac, Pessac, 33604, France
Hôpital Pontchaillou

Rennes, Rennes, 35033, France
Hôpital Robert Debré

Reims, Reims, 51100, France
Hôpital Saint Eloi

Montpellier, Montpellier, 34295, France
Hôpital Saint-Louis

Paris, PARIS, 75475, France
Hôpital St André

Bordeaux, Bordeaux, 33075, France
Hôpital de la Timone

Marseille, Marseille, 13885, France
Hôpitaux de Brabois

Vandœuvre-lès-Nancy, Vandoeuvre LES Nancy, 54500, France
Institut Gustave Roussy

Villejuif, Villejuif, 94805, France

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