New microscope could help surgeons spot hidden skin cancer in real time

NCT ID NCT05814900

Completed Diagnosis Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special microscope (two photon microscopy) can detect leftover basal cell carcinoma during Mohs surgery as accurately as the usual lab method. 135 people having Mohs surgery for skin cancer took part. The goal was to see if the new imaging tool could give surgeons faster, reliable results about whether all cancer cells were removed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: two photon microscopy imaging device
What this could lead to: If it works, this could give surgeons a faster, more accurate way to check if all cancer has been removed during Mohs surgery.
What could go wrong: This is a small, completed study comparing a new imaging method to standard lab slides. The new method may not be as reliable or practical for everyday use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BASAL CELL CARCINOMA

Contacts and locations

Locations

Rochester Dermatologic Surgery

Victor, New York, 14654, United States

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