New microscope could help surgeons spot hidden skin cancer in real time

NCT ID NCT05814900

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special microscope (two photon microscopy) can detect leftover basal cell carcinoma during Mohs surgery as accurately as the usual lab method. 135 people having Mohs surgery for skin cancer took part. The goal was to see if the new imaging tool could give surgeons faster, reliable results about whether all cancer cells were removed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

two photon microscopy imaging device

What this could lead to

If it works, this could give surgeons a faster, more accurate way to check if all cancer has been removed during Mohs surgery.

What could go wrong

This is a small, completed study comparing a new imaging method to standard lab slides. The new method may not be as reliable or practical for everyday use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rochester Dermatologic Surgery

    Victor, New York, 14654, United States