New drug BL-M14D1 enters first human tests for tough cancers

NCT ID NCT06505824

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase study tests a new drug called BL-M14D1 in 22 adults with advanced small cell lung cancer, neuroendocrine tumors, or other solid cancers that have not responded to standard treatments. The drug is given by IV every 3 weeks. The main goals are to check safety, find the right dose, and get a first look at whether it can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BL-M14D1 (a drug given by IV infusion every 3 weeks)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced small cell lung cancer or neuroendocrine tumors who have run out of standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 22 participants, so the main goal is safety and dosing, not proof of effectiveness. The drug may cause side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm neuroendocrine neoplasm small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai East Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact