New liposomal drug takes on advanced cancers
NCT ID NCT06526819
First seen Jun 25, 2026 · Last updated Aug 13, 2026 · Updated 5 times
Summary
This study tests an experimental drug called SMP-3124LP, which is a liposomal (fat-encapsulated) version of a cancer-fighting compound. It is for adults with advanced solid tumors that have not responded to standard treatments. The trial has two parts: first, finding the safest dose, and second, checking how well it shrinks tumors. About 120 people will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SMP-3124LP (a liposomal formulation of an experimental drug)
- What this could lead to
- If it works, this could point toward a new treatment option for people with advanced solid tumors that have stopped responding to standard therapies.
- What could go wrong
- This is an early-phase trial with only 120 participants, so the drug may not prove effective or safe enough for wider use. Side effects are unknown and could be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advent Health
RECRUITINGCelebration, Florida, 32804, United States
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Cedars Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
Contact Email: •••••@•••••
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Kyoto University Hospital
RECRUITINGKyoto, 606-8507, Japan
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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National Cancer Center Hospital East
RECRUITINGKashiwa-shi, 277-8577, Japan
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Northwestern Medicine Cancer Center
RECRUITINGChicago, Illinois, 60611, United States
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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Sarah Cannon Research Institute at HealthOne
RECRUITINGDenver, Colorado, 80218, United States
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The University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
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University of Washington
RECRUITINGSeattle, Washington, 98105, United States
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Vanderbilt-Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
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