Immunotherapy hope for rare Gene-Mutated cancers
NCT ID NCT03810339
First seen Apr 23, 2026 · Last updated Apr 25, 2026 · Updated 1 time
Summary
This study tests a drug called toripalimab, which helps the immune system fight cancer. It is for people with advanced solid tumors that have specific gene changes (POLE or POLD1 mutations) but not high microsatellite instability. About 35 adults who have not responded to standard treatments will receive the drug to see if their tumors shrink or stop growing.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cancer center of Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510060, China
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated Hospital of Guizhou Medical University
RECRUITINGGuiyang, Guizhou, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Dalian Medical University
RECRUITINGDalian, Liaoning, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.