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New combo therapy aims to shrink Hard-to-Treat tumors

NCT ID NCT07392736

Recruiting now Disease control Sponsor: Advenchen Laboratories, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two drugs, AL8326 and toripalimab, together in people with advanced solid tumors that have not responded to standard treatments. The goal is to find the best dose and see if the combination can shrink tumors. About 228 adults will take part in this early-phase trial.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOR

Contacts and locations

Locations

  • Cancer Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, 515000, China

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, 350001, China

  • Guangxi Medical University Cancer Hospital

    RECRUITING

    Nanning, Guangxi, 530021, China

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, 450000, China

  • Hunan Cancer Hospital

    RECRUITING

    Hunan, Changsha, 410000, China

  • Liuzhou Workers' Hospital

    RECRUITING

    Liuzhou, Guangxi, China

  • National GCP Center for Anticancer Drugs,The Independent Ethics Committee

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact Email: •••••@•••••

  • SIR RUN RUN SHAW Hospital Zhejiang University School Of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310016, China

  • The Cancer Hospital of the Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact Email: •••••@•••••

  • The First Affiliated Hospital of Guilin Medical Universty

    RECRUITING

    Guilin, Guangxi, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    RECRUITING

    Xi’an, Shanxi, 710000, China

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 450000, China

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    RECRUITING

    Nanning, Guangxi, 530000, China

  • Yuebei People's Hospital

    RECRUITING

    Shaoguan, Guangdong, 51200, China

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

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