New combo therapy aims to wake up immune system against stubborn cancers

NCT ID NCT05338658

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 20 times

Summary

This early-phase study tests a new approach called peptide alarm therapy (PAT) given as an injection directly into tumors, along with a standard immunotherapy drug, for people with advanced solid tumors that have stopped responding to at least one prior treatment. The goal is to find the safest dose and see if the combination can help control the cancer. About 21 adults who have had certain past infections (CMV and EBV) and a specific genetic marker (HLA-A*0201) are eligible to join.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Masonic Cancer Center at University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact

Conditions

Explore the condition pages connected to this study.