Masonic Cancer Center, University Of Minnesota

This study is testing a specific type of stem cell transplant using donated umbilical cord blood to treat patients with serious blood cancers and disorders. The procedure involves high-dose chemotherapy and radiation to wipe out the patient's diseased bone marrow before infusing …

This study is testing whether adding a special gut bacteria supplement (called restorative microbiota therapy) to standard chemotherapy and immunotherapy drugs helps people with advanced lung cancer live longer without their cancer getting worse. About 82 participants will be ran…

This study is testing a stem cell transplant procedure that does not use radiation to prepare the body. It aims to control Hodgkin and non-Hodgkin lymphoma in patients whose cancer has returned or is hard to treat, including people living with HIV. Researchers will compare how lo…

This trial is testing a treatment for patients whose first bone marrow or stem cell transplant failed. The goal is to help a second transplant from a partially matched family donor successfully take hold and grow. The treatment uses a combination of chemotherapy and low-dose radi…

This early-stage trial is testing whether a modified immune cell therapy called FT536 can help control recurrent ovarian, fallopian tube, or primary peritoneal cancers. Participants receive chemotherapy followed by FT536 delivered directly into the abdomen through a temporary cat…

This study is testing a donor stem cell transplant to treat people with severe inherited blood disorders like sickle cell disease and thalassemia, who currently depend on regular blood transfusions. The goal is to replace the patient's faulty blood-making system with a healthy do…

This study is testing a two-part, high-dose chemotherapy treatment followed by two separate stem cell transplants for children and young adults with high-risk neuroblastoma. The goal is to better control the cancer and prevent it from coming back after initial treatment. Research…

This study is testing a modified stem cell transplant procedure for people with inherited bone marrow failure disorders like Fanconi anemia. The goal is to see if removing specific immune cells from the donor cells before transplant can reduce the risk of a serious complication c…

This early-stage study is testing whether lab-grown muscle stem cells are safe when injected into the foot muscles of adults with Duchenne muscular dystrophy (DMD). Researchers will give eight non-walking adults a single injection and monitor them closely for side effects. The ma…

This early-stage study is testing the safety of a new experimental injection called Peptide Alarm Therapy (PAT) when given directly into tumors alongside standard immunotherapy. It's for adults with advanced solid tumors that have continued to grow despite one or more prior treat…

This early-stage study is testing a modified virus designed to infect and destroy pancreatic cancer cells when injected directly into tumors. Researchers are looking for the highest safe dose in 18 patients whose cancer is still confined to the pancreas area. The virus is deliver…

This study tests the safety of using unlicensed cord blood units for patients with blood cancers who need stem cell transplants. Researchers want to make sure these cord blood units don't transmit infections or cause serious reactions during infusion. The trial will track 250 pat…

This study is testing whether connecting caregivers of colorectal cancer patients with free legal services can help reduce their stress and financial strain. The pilot program will provide personalized legal care to 20 patient-caregiver pairs for 3 months. Researchers will measur…

This study is testing if a newer pain control method works as well as the current standard for patients having major pancreas surgery. The new method involves injecting long-lasting numbing medicine into the abdominal wall (a rectus sheath block), while the standard method uses a…

This study is testing a new digital tool called SALSA to see if it can spot thinking and memory problems early in cancer patients receiving a powerful immunotherapy called CAR-T. Researchers will compare the tool to standard check-ups in about 38 adults getting CAR-T treatment in…

This study aims to understand why young survivors of leukemia, chronic lung disease from prematurity, and heart transplants often struggle with exercise. Researchers will measure heart and lung function during bike workouts in 90 participants aged 8-25. The goal is to gather data…

This study aims to understand if relighting a cigarette produces more harmful chemicals than smoking it without stopping. Researchers will observe 30 adult smokers who regularly relight cigarettes, measuring the smoke they produce and asking about their experience. The goal is to…

This study aims to understand what harmful chemicals firefighters absorb when fighting building fires. Researchers will collect urine and cheek cell samples from 60 firefighters before a fire call, then again within 24 hours and one week after. By comparing these samples, they ho…