Masonic Cancer Center, University Of Minnesota

This early-stage trial is testing whether adding an experimental drug called E7777 before standard CAR-T cell therapy can improve results for adults with aggressive B-cell lymphomas that have returned or not responded to prior treatments. The drug aims to help the CAR-T cells wor…

This early-stage study is testing whether daily supplements of curcumin (from turmeric) and special high-phenolic olive oil are safe and might help control skin tumors in adults with neurofibromatosis type 1 (NF1). The 23 participants take the supplements twice daily for up to a …

This study is testing whether specially grown cord blood stem cells can help patients with high-risk blood cancers recover their immune systems faster after a transplant. Participants receive a transplant using these expanded stem cells after strong chemotherapy. Researchers are …

This study is testing a treatment to rebuild the immune system in people with severe inherited immune deficiencies. Patients receive stem cells from a donor, which are meant to grow into healthy new immune cells. The goal is to control the disease and reduce life-threatening infe…

This early-stage study is testing whether giving two existing drugs—dexamethasone (into the spine) and simvastatin (a pill)—can safely prevent or reduce serious brain-related side effects in adults with lymphoma receiving a powerful treatment called CAR-T cell therapy. The main g…

This study aims to understand how a drug called laronidase works in very young children with a rare genetic disorder (MPS I) who are getting a stem cell transplant. Researchers will observe and measure the drug levels in the blood before and after the transplant. The children wil…

This study is testing a stem cell transplant procedure for children and adults with severe, inherited metabolic disorders and a rare bone disease. The goal is to see if using a specific drug combination can help the donor cells successfully take hold in the patient's body while k…

This study is testing several FDA-approved CAR-T cell therapies for patients whose blood cancers have returned or not responded to standard treatments. It involves about 150 participants with conditions like acute lymphoblastic leukemia and various lymphomas. The main goals are t…

This small, early-stage study is testing whether taking kava, a plant-based supplement, can safely help reduce anxiety and stress in people who have finished cancer treatment. Participants take either kava or a placebo pill for two weeks, then switch after a break. The study is c…

This study aims to measure how much time people with metastatic breast or advanced ovarian cancer spend on treatment-related activities like appointments, travel, medication management, and paperwork. Participants carry a smartphone for 28 days to track their activities and compl…

This study aims to understand the health impact of switching from cigarettes to a specific, standardized e-cigarette. Researchers are measuring levels of nicotine and other chemicals in the bodies of 47 adult smokers before and after they switch. The goal is to gather initial dat…

This study aims to understand how a specific chemical (nornicotine) found in smokeless tobacco products might turn into a known cancer-causing agent (NNN) inside the user's body. Researchers are enrolling 55 adult smokeless tobacco users to measure these chemicals in their urine.…