Can a statin and steroid shield the brain during lymphoma treatment?
NCT ID NCT04514029
First seen Jan 09, 2026 · Last updated May 11, 2026 · Updated 17 times
Summary
This study tests whether giving two drugs—simvastatin (a cholesterol pill) and dexamethasone (a steroid injected into the spine)—can safely prevent or reduce brain-related side effects from a powerful lymphoma cell therapy called axi-cel. About 37 adults with certain types of B-cell lymphoma that did not respond to prior treatments will take part. The main goal is to see if this approach is safe and feasible, not yet to prove it works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Masonic Cancer Center, University of Minnesota
Minneapolis, Minnesota, 55455, United States
Conditions
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