Engineered immune cells take on tough blood cancers in phase 2 trial

NCT ID NCT03642626

First seen Jan 29, 2026 · Last updated Apr 24, 2026 · Updated 10 times

Summary

This study tests FDA-approved CAR-T cell therapy in 150 people with certain blood cancers (acute lymphoblastic leukemia or large B-cell lymphoma) that did not respond to standard treatment or returned. Participants receive their own immune cells that have been reprogrammed to attack cancer. The main goal is to see how many patients achieve complete or partial remission, while monitoring side effects like severe neurological reactions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Masonic Cancer Center at University of Minnesota

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.