New study tests what happens to your body when you switch from cigarettes to a Lab-Grade E-Cig
NCT ID NCT04003805
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at what chemicals smokers are exposed to when they switch from regular cigarettes to a standardized research e-cigarette (SREC). About 47 adult smokers who smoke at least 5 cigarettes daily will stop smoking and use only the SREC for a period. Researchers will measure nicotine and other harmful substances in their urine and saliva to understand how switching affects exposure to toxins and potential cancer-causing agents.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Standardized Research E-cigarette (SREC) with nicotine e-liquid
What this could lead to
If successful, this study could provide reliable data on how switching from cigarettes to a standardized e-cigarette changes exposure to harmful chemicals, helping to inform future tobacco harm reduction strategies.
What could go wrong
This is a small, early-phase study (47 participants) focused on measuring biomarkers, not health outcomes. Results may not apply to real-world e-cigarettes, which vary widely. The study does not test whether e-cigarettes are safe or effective for quitting smoking.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Minnesota, Masonic Cancer Center
Minneapolis, Minnesota, 55455, United States