Stem cell transplant offers new hope for kids with rare immune diseases

NCT ID NCT01652092

Ongoing Disease control Sponsor: Masonic Cancer Center, University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a donor stem cell transplant for people with severe immune system problems, like SCID and Wiskott-Aldrich syndrome. The goal is to help the body make healthy blood cells and fight infections. Participants receive donated stem cells to rebuild their immune system. The study tracks how well the new cells take hold and if there are any complications.

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Conditions

The condition(s) this trial relates to.

Chediak-Higashi syndrome chronic granulomatous disease common variable immunodeficiency Griscelli syndrome hemophagocytic syndrome Histiocytosis, Langerhans-Cell hyper-IgM syndrome hyper-IgM syndrome type 1 inborn error of immunity Langerhans cell histiocytosis Lymphohistiocytosis, Hemophagocytic lymphoproliferative syndrome MHC class II deficiency Omenn syndrome reticular dysgenesis severe combined immunodeficiency Wiskott-Aldrich syndrome X-linked lymphoproliferative syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BARE LYMPHOCYTE SYNDROME CD40 LIGAND DEFICIENCY CHEDIAK-HIGASHI SYNDROME CHRONIC GRANULOMATOUS DISEASE COMMON VARIABLE IMMUNODEFICIENCY GRISCELLI SYNDROME HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS HYPER IGM SYNDROME LANGERHAN'S CELL HISTIOCYTOSIS OMENN'S SYNDROME RETICULAR DYSGENESIS SCID WISKOTT-ALDRICH SYNDROME X-LINKED LYMPHOPROLIFERATIVE DISEASE

Contacts and locations

Locations

Masonic Cancer Center, University of Minnesota

Minneapolis, Minnesota, 55455, United States

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