COMMON VARIABLE IMMUNODEFICIENCY
Clinical trials for COMMON VARIABLE IMMUNODEFICIENCY explained in plain language.
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Could a stem cell transplant cure immune diseases?
⭐️ CURE ⭐️ Recruiting nowThis study tests whether a stem cell transplant can cure people with serious immune system disorders. Participants, aged 4 to 69, receive healthy donor stem cells to rebuild their immune system. The goal is to see if the transplant can permanently fix the immune defect and elimin…
Matched conditions: COMMON VARIABLE IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: ⭐️ CURE ⭐️
Last updated Jun 27, 2026 12:28 UTC
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Can a donor stem cell transplant fix broken immune systems?
Disease control Recruiting nowThis study tests whether a stem cell transplant from a healthy donor can help people with severe primary immunodeficiencies. Participants aged 4 to 75 receive chemotherapy before the transplant to prepare their body. The goal is to see if the procedure is safe and can improve imm…
Matched conditions: COMMON VARIABLE IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Breathing test could help doctors personalize antibody therapy for immune deficiency
Disease control Recruiting nowThis study looks at whether a simple breathing test (spirometry) can help doctors decide the right dose of immunoglobulin therapy for people with common variable immune deficiency (CVID). Researchers will enroll 22 adults with CVID who already take a stable dose of Hizentra. Half…
Matched conditions: COMMON VARIABLE IMMUNODEFICIENCY
Phase: PHASE4 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Immune-Calming drug shows promise for rare lung complication
Disease control Recruiting nowThis phase 2 trial tests whether abatacept (Orencia) can improve lung disease in people with common variable immunodeficiency (CVID). About 38 children and adults will receive either the drug or a placebo for 6 months. The main goal is to see if lung damage on CT scans shrinks by…
Matched conditions: COMMON VARIABLE IMMUNODEFICIENCY
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Scientists seek hidden causes of chronic lung infections
Knowledge-focused Recruiting nowThis study follows 900 people with bronchiectasis—a condition where airways are damaged and prone to infection—to learn why they get sick repeatedly. Researchers will collect medical history, lung function tests, and blood, urine, and sputum samples from patients and their family…
Matched conditions: COMMON VARIABLE IMMUNODEFICIENCY
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Scientists launch Long-Term study to unravel mysterious liver disease
Knowledge-focused Recruiting nowThis study is observing 400 people aged 12 and older who have noncirrhotic portal hypertension (NCPH) or are at risk for it. NCPH is a liver condition that increases blood pressure in the liver's blood vessels without causing cirrhosis, and often has no early symptoms. Researcher…
Matched conditions: COMMON VARIABLE IMMUNODEFICIENCY
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC