Could a stem cell transplant cure immune diseases?

NCT ID NCT04339777

Recruiting now ⭐️ CURE ⭐️ Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a stem cell transplant can cure people with serious immune system disorders. Participants, aged 4 to 69, receive healthy donor stem cells to rebuild their immune system. The goal is to see if the transplant can permanently fix the immune defect and eliminate the disease.

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Conditions

The condition(s) this trial relates to.

autoimmune disease autoimmune lymphoproliferative syndrome common variable immunodeficiency immune system disorder inborn error of immunity lymphoproliferative syndrome Opportunistic Infections T cell immunodeficiency primary T-cell immunodeficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE LYMPHOPROLIFERATIVE COMMON VARIABLE IMMUNODEFICIENCY IMMUNE SYSTEM DISEASES LYMPHOPROLIFERATIVE DISORDERS PRIMARY T-CELL IMMUNODEFICIENCY DISORDERS

Contacts and locations

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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