Tiny study tracks enzyme levels in kids with rare disease before and after transplant

NCT ID NCT05634512

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This study looks at how children with a rare genetic disease called MPS IH process the enzyme drug laronidase before and after a stem cell transplant. Researchers will collect blood samples from 13 children up to 3 years old to see how factors like body size affect drug levels. The goal is to learn more about how the transplant changes the way the drug works, which may help doctors give the right dose in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Minnesota Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.