New study aims to uncover heart risks in rare MPS diseases

NCT ID NCT07361536

Recruiting now Knowledge-focused Sponsor: Children's Hospital of Orange County Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how heart and blood vessel problems develop in people with MPS I and IVA. Over 4 years, 240 participants will get yearly heart ultrasounds, blood tests, and urine tests. The goal is to find reliable markers that can track heart health and guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors detect heart problems earlier in people with MPS and guide future treatments.
What could go wrong: This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MPS - MUCOPOLYSACCHARIDOSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

mucopolysaccharidosis mucopolysaccharidosis I, dog Mucopolysaccharidosis IV mucopolysaccharidosis type 1 mucopolysaccharidosis type 4A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MPS - MUCOPOLYSACCHARIDOSIS MPS I MPS IV A MPS IVA

Contacts and locations

Locations

Children'S Hospital of Orange County
RECRUITING

Orange, California, 92868, United States
Saint Louis University
NOT_YET_RECRUITING

St Louis, Missouri, 63104, United States
University of Minnesota
NOT_YET_RECRUITING

Minneapolis, Minnesota, 55455, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.