New scan technique could spot lung trouble early in transplant patients

NCT ID NCT05866302

Recruiting now Knowledge-focused Sponsor: University of Michigan Rogel Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a special CT scan analysis called parametric response mapping (PRM) can detect early signs of chronic lung disease in people who have had a stem cell transplant. Researchers will follow 375 patients for one year to see if PRM patterns predict lung function decline or survival. The goal is to improve monitoring and timing of treatment for lung complications after transplant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a new way to predict lung problems early in transplant patients, helping doctors intervene sooner.
What could go wrong: This is an observational study, not testing a treatment. It may not lead to direct benefits for participants, and the imaging technique might not prove reliable in larger groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bronchiolitis obliterans syndrome chronic graft versus host disease chronic obstructive pulmonary disease graft versus host disease restrictive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LUNG DISEASE GRAFT-VERSUS-HOST DISEASE HEMATOPOIETIC CELL TRANSPLANTATION

Contacts and locations

Locations

Dana Farber
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States
Emory University
NOT_YET_RECRUITING

Atlanta, Georgia, 30322, United States
Fred Hutchinson Cancer Research Center
RECRUITING

Seattle, Washington, 98109, United States
MD Anderson
NOT_YET_RECRUITING

Houston, Texas, 77030, United States
Stanford Hospital
RECRUITING

Stanford, California, 94305, United States
The University of Michigan Cancer Center
RECRUITING

Ann Arbor, Michigan, 48109, United States

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