Could a Pre-Treatment drug make CAR-T therapy more effective for tough lymphomas?

NCT ID NCT04855253

First seen Jan 15, 2026 · Last updated May 12, 2026 · Updated 19 times

Summary

This study tests whether adding a drug called E7777 before standard CAR-T cell therapy can help people with relapsed or hard-to-treat large B-cell lymphoma. About 30 adults will receive E7777 followed by chemotherapy and an approved CAR-T product. The goal is to find the safest dose and see if it improves cancer control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Minnesota, Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.