New stem cell approach aims to beat lymphoma without radiation
NCT ID NCT03125642
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 study tests a stem cell transplant procedure for people with Hodgkin or non-Hodgkin lymphoma, including those with HIV. Participants receive high-dose chemotherapy followed by an infusion of their own stem cells. The goal is to see if this radiation-free approach can improve survival and reduce side effects compared to older methods.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- chemotherapy (etoposide, carmustine, cytarabine, melphalan) followed by stem cell transplant
- What this could lead to
- If successful, this approach could offer a better, radiation-free way to control lymphoma and improve long-term survival for patients, including those with HIV.
- What could go wrong
- This is a mid-stage trial with only 150 participants, so results may not apply to everyone. The chemotherapy has serious side effects, and the transplant carries risks like infection and organ damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Masonic Cancer Center, University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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