Can a new Liposome-Wrapped drug shrink Hard-to-Treat solid tumors?

NCT ID NCT06234098

Recruiting now Disease control Sponsor: Alyssum Therapeutics Source: ClinicalTrials.gov ↗

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial is testing an experimental drug called AT-1965 in people with advanced solid tumors that have stopped responding to standard treatments. The study has two parts: first, finding a safe dose, and then seeing whether the drug can shrink tumors. About 100 participants will receive weekly intravenous infusions of AT-1965.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: an experimental drug called AT-1965, given as a liposome injection into a vein
What this could lead to: If it works, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong: This is an early, first-in-human trial, so the drug may not be safe or effective. Side effects are unknown, and the chance of benefit is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOR

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CBCC Global Research Site 001
RECRUITING

Scottsdale, Arizona, 85258, United States
CBCC Global Research Site 002
RECRUITING

Portland, Oregon, 97239, United States
CBCC Global Research Site 003
RECRUITING

Stanford, California, 94305, United States
CBCC Global Research Site 005
WITHDRAWN

Bakersfield, California, 93309, United States
CBCC Global Research Site 006
RECRUITING

Dallas, Texas, 75230, United States
CBCC Global Research Site 007
RECRUITING

El Segundo, California, 90245, United States
CBCC Global Research Site 008
RECRUITING

Santa Monica, California, 90403, United States
CBCC Global Research Site 009
RECRUITING

Santa Monica, California, 90404, United States
CBCC Global Research Site 010
NOT_YET_RECRUITING

New York, New York, 10065, United States

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