Experimental pill ICP-723 enters human trials for Hard-to-Treat cancers
NCT ID NCT04685226
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests an experimental oral drug called ICP-723 in people with advanced solid tumors that cannot be removed by surgery. The trial includes both adults and adolescents (ages 12 and up). The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About 310 participants will take part across multiple centers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ICP-723 (an experimental oral tablet)
What this could lead to
If successful, this could point toward a new treatment option for people with advanced solid tumors that are hard to treat.
What could go wrong
This is an early-phase trial (Phase I/II) focused on safety and dosing, so it is not yet known if ICP-723 will effectively shrink tumors or improve survival. Side effects are possible and being closely monitored.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated Cancer Hospital of Shandong First Medical University
RECRUITINGJinan, Shandong, China
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Affiliated Hospital of Jiangnan University
RECRUITINGWuxi, Jiangsu, 214000, China
Contact Phone: •••-•••-••••
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Affiliated Hospital of Qingdao University
RECRUITINGQingdao, Shandong, 266000, China
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Cancer Hospital Affiliated to Guangzhou Medical University
RECRUITINGGuangzhou, Guangdong, 510000, China
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Cancer Hospital Affiliated to Harbin Medical University
RECRUITINGHarbin, Heilongjiang, 150000, China
Contact Phone: •••-•••-••••
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Henan Cancer Hospital
RECRUITINGZhengzhou, Henan, 450000, China
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Henan Provincial People's Hospital
RECRUITINGZhengzhou, Henan, 450000, China
Contact Phone: •••-•••-••••
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Hunan Cancer hospital
RECRUITINGChangsha, Hunan, 410000, China
Contact Phone: •••-•••-••••
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Jiangsu Provincial People's Hospital
RECRUITINGNanjing, Jiangsu, 210000, China
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Peking University Cancer Hospital
RECRUITINGBeijing, Beijing Municipality, 100081, China
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Shanxi Cancer Hospital
RECRUITINGTaiyuan, Shanxi, 030000, China
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Shijiazhuang People's Hospital
RECRUITINGShijiazhuang, Hebei, 050000, China
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Sun Yat-Sen University Cancer Center
RECRUITINGGuangdong, Guangzhou, 510060, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sun Yat-sen Memorial Hospital, Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510000, China
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The Fifth Affiliated Hospital of Sun Yat-sen University
RECRUITINGZhuhai, Guangdong, 519000, China
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The First Affiliated Hospital of Henan University of Science and Technology
RECRUITINGLuoyang, Henan, 471000, China
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The First Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, 330000, China
Contact Phone: •••-•••-••••
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, 450000, China
Contact Phone: •••-•••-••••
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The First Medical Center of the Chinese People's Liberation Army General Hospital
RECRUITINGBeijing, Beijing Municipality, 100081, China
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The Second Affiliated Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, 230000, China
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The first affiliated hospital Zhejiang university school of medicine
RECRUITINGHangzhou, Zhejiang, 310003, China
Contact Phone: •••-•••-••••
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Union Hospital, Tongji Medical College,Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430000, China
Contact Phone: •••-•••-••••
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Yunnan Cancer Hospital
RECRUITINGKunming, Yunnan, 650000, China
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Zhejiang Cancer Hospital
RECRUITINGHangzhou, Zhejiang, ,310000, China
Contact