New pill shows promise in early trial for Hard-to-Treat cancers

NCT ID NCT06212076

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study tests a new drug called IPG1094 in 60 people with advanced solid tumors that cannot be removed by surgery. The drug works by blocking a protein called MIF, which may help slow cancer growth. The trial has two parts: first, finding the safest dose, then seeing if the drug can shrink tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
IPG1094 (a MIF inhibitor tablet)
What this could lead to
If it works, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.
What could go wrong
This is an early phase 1/2 trial with only 60 participants, so it is too soon to know if IPG1094 is safe or effective. The drug may cause side effects or fail to shrink tumors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai General Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200080, China

  • Shanghai GoBroad Cancer Hospital China Pharmaceutical University

    RECRUITING

    Shanghai, China

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