SOLID TUMOR

This study is testing whether the drug olaparib can help control recurrent triple-negative breast cancer in patients who don't have the typical BRCA gene mutations. The trial will enroll 30 women with advanced breast cancer that has returned or spread. Researchers want to see if …

This is an early safety study for a new drug called BSI-082, designed for adults with advanced solid tumors that have spread or stopped responding to standard treatments. The study has two parts: first testing BSI-082 alone at increasing doses, then testing it combined with anoth…

This early-phase study is testing a new type of cell therapy called TCR-T for people with advanced solid tumors that have specific KRAS gene mutations. It aims to see if it is safe and if it can help control the cancer. The treatment involves collecting a patient's own immune cel…

This study is testing a new drug called atamparib to see if it is safe and can help control advanced solid tumors, especially a type of lung cancer. It will involve about 178 adults whose cancer has continued to grow despite standard treatments. The research will first find the s…

This is the first human study of an experimental radioactive drug called RYZ401 for people with advanced neuroendocrine tumors and other solid tumors that have a specific marker. The main goals are to find the safest and most effective dose, check for side effects, and see if the…

This study is testing a new drug called ZGGS34 for people with advanced solid tumors that have stopped responding to standard treatments. The first part checks how safe different doses are, while the second part looks at whether the drug helps shrink tumors in people whose cancer…

This early-stage clinical trial is testing a new drug called HRS-8364 in adults with advanced solid tumors that have progressed despite standard treatments. The study aims to find a safe and effective dose and see if the drug can shrink tumors. It will enroll up to 282 participan…

This early-stage clinical trial is testing a new personalized mRNA vaccine designed to teach the immune system to attack a specific protein found in a patient's tumor cells. The vaccine is given in combination with an existing immunotherapy drug (anti-PD-1) to boost the body's ca…

This early-stage study is testing a new combination of two drugs for people with advanced solid tumors that have stopped responding to standard immunotherapy. The goal is to find the safest and most effective dose of the drug 5-Azacitidine when added to a patient's current immuno…

This study is testing if a natural product made from freeze-dried miracle fruit can help people who are having taste problems from their cancer treatment. About 45 adults with solid tumor cancers will take the berry product up to four times a day before meals for 90 days. Researc…

This study is building a large collection of tissue and blood samples from people with hereditary cancers or a family history of cancer. The goal is to create lab models from these samples to better understand how these cancers work and to help scientists develop new treatments i…