New radioactive 'Theranostic' drugs aim to find and treat brain tumors
NCT ID NCT07178938
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests special radioactive drugs that can both find and treat solid tumors that have spread to the brain. Ten adults with advanced breast cancer and active brain metastases will receive a single dose of a diagnostic agent to see if it lights up the brain tumors on a scan. If it does, they may then receive a therapeutic version to shrink the tumors. The goal is to see if this approach is safe and effective for controlling brain metastases.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiotracer targeting somatostatin receptor 2 ([68Ga]Ga-DOTA-TOC)
- What this could lead to
- If successful, this could lead to a new way to both detect and treat brain metastases from solid tumors, potentially improving outcomes for patients with limited options.
- What could go wrong
- This is a very early, small trial with only 10 participants, so results may not apply to everyone. The treatment involves radioactive drugs, which carry risks like radiation exposure, and it may not work for all tumor types.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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