New hope for hard-to-treat breast cancer? olaparib trial targets BRCA-negative patients

NCT ID NCT05522491

First seen Jan 03, 2026 · Last updated May 06, 2026 · Updated 17 times

Summary

This study tests the drug olaparib in 30 women with recurrent or metastatic triple-negative breast cancer that has a specific genetic change (BRCA1 promoter methylation) but no BRCA1/2 mutations. The goal is to see if the drug can shrink tumors or slow cancer growth. Participants will receive olaparib and be monitored for response and side effects.

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