Can zapping a few tumor spots extend cancer treatment success?

NCT ID NCT07545486

Not yet recruiting Disease control Sponsor: Chirec Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at whether using local ablative therapy (like radiation or surgery) on a limited number of tumor spots can improve outcomes for patients with solid tumors that responded to initial chemotherapy. The researchers will enroll over 1,200 patients with various cancer types and compare their response duration to historical data. The goal is to see if this approach can delay disease progression and improve survival, while also tracking side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: local ablative therapy (LAT)
What this could lead to: If successful, this approach could extend the time patients with certain solid tumors remain progression-free after initial treatment, potentially improving survival.
What could go wrong: This is a proof-of-concept study, not yet recruiting, and results are compared to historical data, not a control group. Local ablative therapy carries risks of serious side effects, including fatal complications.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOR

Contacts and locations

Locations

American University of Beirut (AUB)

Beirut, Lebanon
Bank of Cyprus Oncology

Nicosia, 2006, Cyprus
CHIREC Hospital

Brussels, 1160, Belgium
CHU Brugmann

Brussels, 1020, Belgium
CHU de Saint-Etienne

Saint-Priest-en-Jarez, 42270, France
Centre de Lutte contre le Cancer François Baclesse

Caen, 14000, France
Cliniques Universitaires Saint-Luc

Brussels, 1200, Belgium
Grand Hôpital de Charleroi, site Notre Dame

Charleroi, 6000, Belgium
HELORA Hôpital de Mons - Site Kennedy

Mons, 7000, Belgium
Hôpital Universitaire de Strasbourg

Strasbourg, 67200, France
Institut Paoli-Calmettes

Marseille, 13009, France
Oslo University Hospital / The Norwegian Radium Hospital

Oslo, Norway

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