New pill HQP1351 enters human testing for stubborn cancers

NCT ID NCT03594422

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing an oral drug called HQP1351 in about 100 people with advanced gastrointestinal stromal tumors (GIST) or other solid tumors. The main goal is to find a safe dose and see how the body handles the drug. Participants take the pill every other day for four weeks per cycle. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HQP1351 (oral drug)

What this could lead to

If successful, this could help determine a safe dose of HQP1351 for future studies in treating GIST and other solid tumors.

What could go wrong

This is an early Phase 1 trial focused on safety and dosing, not yet on effectiveness. The drug may not work or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GASTROINTESTINAL STROMAL TUMOR (GIST) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

gastrointestinal stromal tumor neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chinese PLA general hospital, Beijing, China

    RECRUITING

    Beijing, China

    Contact

    Contact

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, China

    Contact

    Contact

  • Guangdong general hospital

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

    Contact

  • Henan cancer hospital

    RECRUITING

    Zhengzhou, Henan, China

    Contact

    Contact

    Contact

  • Sun-Yat Sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Union Hospital Tongji Medical College of Huazhong University of Science ang Technology

    RECRUITING

    Wuhan, Hubei, 215316, China

    Contact

    Contact