New microscope peers inside living tumors to see how they behave

NCT ID NCT03823144

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses a special microscope called intravital microscopy to look at blood vessels inside solid tumors while patients are in surgery. Researchers want to see how these vessels work and how well they let blood and dye flow through. The goal is to learn whether tumor vessel function could help predict how well a patient might respond to cancer treatments. About 85 adults with various cancers, including breast, colorectal, and pancreatic, will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Fluorescein Sodium Injection
What this could lead to
If successful, this could help doctors predict which patients' tumors are likely to respond to certain cancer treatments based on how their blood vessels function.
What could go wrong
This is an early observational study, not a treatment trial. It may not lead to any direct benefit for participants, and the findings may not apply to all cancer types.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic Florida

    RECRUITING

    Jacksonville, Florida, 32224, United States

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