Tailor-Made vaccine aims to train immune system against cancer
NCT ID NCT07680582
First seen Jul 02, 2026 · Last updated Aug 04, 2026 · Updated 2 times
Summary
This early-phase trial is testing a personalized cancer vaccine (ABO2109) combined with an immunotherapy drug (toripalimab) in people with solid tumors. The vaccine is custom-made for each patient to target their specific cancer. The study aims to check the safety of this combination and see how well it triggers an immune response. Participants include those who have had surgery for their cancer or have advanced disease, and the trial will also look for early signs that the vaccine might help prevent the cancer from coming back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- personalized cancer vaccine (ABO2109) and toripalimab (anti-PD-1 antibody)
- What this could lead to
- If successful, this could pave the way for a personalized vaccine that trains the immune system to fight residual cancer cells after surgery, potentially reducing recurrence risk.
- What could go wrong
- This is a very early (Phase 1) study with only 60 participants, so safety and effectiveness are not yet proven. The vaccine is personalized, making it complex and costly, and it may not work for all tumor types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SOLID TUMOR are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 200025, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood test may spare cancer patients unneeded iron infusions
- Peppermint and lemon scents put to the test against chemo nausea
- Can a new drug shield nerves from Chemotherapy's side effects?
- Can a Tumor's DNA guide better cancer care for kids?
- Can a new PET tracer reveal a key cancer target?
- Can a smart drug home in on Hard-to-Treat cancers?