Peppermint and lemon scents put to the test against chemo nausea

NCT ID NCT04560114

NEW Completed Symptom relief Sponsor: Centre Francois Baclesse Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This phase 2 trial tests whether inhaling a blend of peppermint and lemon essential oils can reduce nausea and vomiting in people receiving their first chemotherapy for a solid tumor. Participants will inhale the oils four times daily and whenever nausea strikes, with symptoms tracked over the first days after treatment. The study aims to measure how well this natural approach works as a supportive care option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Inhaled blend of peppermint and lemon essential oils
What this could lead to: If effective, this could offer a safe, natural option to help reduce nausea and vomiting during chemotherapy, improving quality of life for cancer patients.
What could go wrong: This is an early-phase study without a placebo comparison, so results may be inconclusive. Effectiveness is not yet proven, and individual responses to aromatherapy can vary.

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Conditions

The condition(s) this trial relates to.

Nausea neoplasm Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AROMATHERAPY ESSENTIAL OIL NAUSEA AND VOMITING SUPORTIVE CARE

Contacts and locations

Locations

Centre Francois Baclesse

Caen, 14000, France

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