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New targeted drug shows promise for Hard-to-Treat cancers

NCT ID NCT07196644

Recruiting now Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This study tests an experimental drug called telisotuzumab adizutecan in people aged 12 and older whose solid tumors have a specific genetic change (MET amplification). The goal is to see if the drug can shrink tumors and to check for side effects. Participants receive the drug through an IV and are monitored with scans and blood tests.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope National Medical Center /ID# 275613

    RECRUITING

    Duarte, California, 91010, United States

  • Duke Cancer Institute /ID# 275604

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Florida Cancer Specialists - North /ID# 277137

    RECRUITING

    St. Petersburg, Florida, 33705, United States

  • Hadassah Medical Center-Hebrew University /ID# 274343

    RECRUITING

    Jerusalem, 91120, Israel

  • Hokkaido University Hospital /ID# 276333

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Kyoto University Hospital /ID# 276398

    RECRUITING

    Kyoto, Kyoto, 606-8507, Japan

  • Kyushu University Hospital /ID# 276302

    RECRUITING

    Fukuoka, Fukuoka, 812-8582, Japan

  • Memorial Sloan Kettering Cancer Center - New York - York Avenue /ID# 275999

    RECRUITING

    New York, New York, 10065, United States

  • Nagoya University Hospital /ID# 276336

    RECRUITING

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Cancer Center Hospital /ID# 276297

    RECRUITING

    Chuo-Ku, Tokyo, 104-0045, Japan

  • Northwestern University Feinberg School of Medicine /ID# 276436

    RECRUITING

    Chicago, Illinois, 60611-2927, United States

  • Okayama University Hospital /ID# 276299

    RECRUITING

    Okayama, Okayama-ken, 700-8558, Japan

  • Rabin Medical Center. /ID# 274341

    RECRUITING

    Petah Tikva, 4941492, Israel

  • START Midwest /ID# 276603

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • Samsung Medical Center /ID# 275705

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Seoul National University Hospital /ID# 275703

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • South Texas Accelerated Research Therapeutics (START) /ID# 276608

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Start Mountain Region /ID# 276607

    RECRUITING

    West Valley City, Utah, 84119, United States

  • Tel Aviv Sourasky Medical Center /ID# 274344

    RECRUITING

    Tel Aviv, Tel Aviv, 6423906, Israel

  • The Chaim Sheba Medical Center /ID# 274342

    RECRUITING

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The University of Texas MD Anderson Cancer Center /ID# 275663

    RECRUITING

    Houston, Texas, 77030, United States

  • Tohoku University Hospital /ID# 276344

    RECRUITING

    Sendai, Miyagi, 980-8574, Japan

  • University of Chicago Medical Center /ID# 275342

    RECRUITING

    Chicago, Illinois, 60637, United States

  • Valkyrie Clinical Trials /ID# 275547

    RECRUITING

    Los Angeles, California, 90067, United States

  • Yale University School of Medicine /ID# 275978

    RECRUITING

    New Haven, Connecticut, 06510, United States

  • Yonsei University Health System Severance Hospital /ID# 276184

    RECRUITING

    Seoul, Seoul Teugbyeolsi, 03722, South Korea

Conditions

Explore the condition pages connected to this study.

SOLID TUMORS HARBORING MET AMPLIFICATION