Abbvie

This program provides early access to an investigational drug called Elezanumab for people with acute spinal cord injury before it is officially approved. It is for patients who have no other suitable treatment options and cannot join ongoing clinical trials. A doctor must determ…

This study compares a new targeted drug called telisotuzumab vedotin against standard chemotherapy (docetaxel) for adults with advanced non-small cell lung cancer that has worsened after previous treatment. The trial aims to see if the new drug helps patients live longer without …

This study is observing how safe and effective the approved medication upadacitinib is for people with moderate to severe Crohn's disease in real-world Japanese clinics. It will follow about 240 patients for up to 64 weeks as they take the drug as prescribed by their doctor. The …

This study follows 700 adults with moderate-to-severe plaque psoriasis who are already prescribed risankizumab by their doctors. Researchers will track how this treatment affects patients' quality of life and daily experiences over 2.5 years in real-world settings. The study obse…

This program provides eligible patients with access to the drug upadacitinib for conditions like Crohn's disease, ulcerative colitis, and atopic dermatitis before it is officially approved in their country. A doctor must determine if the potential benefits for an individual patie…

This study is testing a new drug, ABBV-706, combined with an existing immunotherapy (atezolizumab) for people with a fast-spreading type of lung cancer who haven't had treatment yet. Researchers want to find the best dose, see if it's safe, and check if it works better than the c…

This study is testing whether a single gene therapy injection can reduce the need for frequent eye injections in people with wet age-related macular degeneration (AMD), a leading cause of vision loss. About 561 participants aged 50+ who have been receiving regular eye injections …

This study is testing the safety and effectiveness of an investigational drug called telisotuzumab vedotin for adults with a specific type of advanced non-small cell lung cancer (NSCLC). The cancer must have a biomarker called c-Met overexpression and must have worsened after pri…

This study is testing three different targeted treatment approaches for adults with moderate to severe rheumatoid arthritis who haven't responded well to previous biologic medications. Approximately 180 participants worldwide will receive either one of two experimental drugs alon…

This study is testing different combinations of an experimental drug called mirvetuximab soravtansine with two other cancer drugs (carboplatin or bevacizumab) for ovarian cancer. It aims to find the safest and most effective doses for patients whose tumors have a specific marker.…

This is an early-stage study to test the safety and effects of an investigational drug called ABBV-295, given as an injection under the skin, in adults with obesity. The main goals are to check for side effects, see how the body processes the drug, and measure any changes in body…

This study is testing two investigational drugs, risankizumab and lutikizumab, to see how well they control the symptoms of active psoriatic arthritis. About 120 adults who have not gotten enough relief from other treatments will receive one drug, the other, or both together. Res…

This study is testing whether a pill called venetoclax can help control a rare type of blood cancer called Waldenström macroglobulinemia in Japanese adults whose cancer has come back or stopped responding to prior treatments. About 14 participants will take the pill daily, with d…

This study is observing how well an approved Parkinson's medication works in real-world German clinics. About 125 adults with advanced Parkinson's who are prescribed Foslevodopa/Foscarbidopa will be followed for up to 12 months. Researchers will track changes in symptoms, quality…

This study is testing four different targeted therapies (risankizumab, trosunilimab, lutikizumab, and ABBV-8736) to see if they can help control moderate to severe Crohn's disease. The trial will enroll about 540 adults worldwide who haven't responded well to standard treatments.…

This is the first study in people testing an experimental drug called ABBV-324 for advanced liver cancer or a type of lung cancer. The main goals are to find a safe dose, see how the body processes the drug, and check if it helps shrink tumors. The study will enroll about 232 adu…

This study is testing whether adding an experimental drug called etentamig to standard treatment works better for newly diagnosed multiple myeloma patients who aren't eligible for stem cell transplant. About 660 adults worldwide will receive either the new combination or current …

This study is testing a surgical mesh material called ARTIA to see if it makes breast reconstruction after mastectomy safer and leads to better results. Researchers will compare outcomes in about 783 women who receive the mesh during their reconstruction surgery to those who don'…

This is the first study in people testing a new drug called ABBV-969 for men with advanced prostate cancer that has spread and no longer responds to standard hormone-blocking treatments. The main goals are to find a safe dose, see how the body processes the drug, and check for ea…

This study is testing whether a daily pill called atogepant can help prevent chronic migraines in teenagers aged 12 to 17. About 420 teens worldwide will take either the real medicine or a placebo (sugar pill) for 12 weeks, and neither they nor their doctors will know which one t…

This large, late-stage study is testing whether an investigational drug called lutikizumab can help control the painful lumps and sores caused by moderate-to-severe hidradenitis suppurativa (HS). About 1280 adults and adolescents with HS will receive either the drug or a placebo …

This study is observing how well an oral medication called upadacitinib works for adults with axial spondyloarthritis, a type of inflammatory arthritis that mainly affects the spine. About 352 participants in Germany will take the medication as prescribed by their doctor for abou…

This large, late-stage study is testing whether the medication upadacitinib can safely control disease activity in adults with moderate-to-severe systemic lupus erythematosus (SLE). About 1000 participants worldwide will take either the study drug or a placebo pill daily for a ye…

This study looks back at real-world medical records to check the safety and effectiveness of an 8-week hepatitis C treatment (Glecaprevir/Pibrentasvir) in people who are also taking other prescription medications or illicit drugs. It aims to see how well the treatment works and w…

This study is observing how well the approved drug risankizumab works for adults with moderate to severe ulcerative colitis in real-world medical settings in Japan. It will follow about 200 patients for up to 3 years as they receive the drug as part of their normal care. The main…

This study is testing whether adding a new investigational drug, telisotuzumab adizutecan, to an approved lung cancer drug (osimertinib) works better than the current standard treatment. It is for adults with a specific type of advanced lung cancer that has spread and has an EGFR…

This study aims to find the safest way to start a combination drug treatment for adults with a common type of blood cancer called chronic lymphocytic leukemia (CLL). Researchers are testing different dosing schedules for the drug venetoclax when given with two other medicines to …

This study is testing if a pill called atogepant can prevent menstrual migraines—the severe headaches some women get around their period. About 430 women with a history of these migraines will take either the real pill or a placebo (sugar pill) for three menstrual cycles to see i…

This study is testing how well and how safe the drug upadacitinib is for children and teenagers (ages 1 to under 18) with a rare and serious form of childhood arthritis called systemic juvenile idiopathic arthritis (sJIA). It will compare upadacitinib to another existing treatmen…

This study is testing whether adding an experimental drug called telisotuzumab adizutecan to standard chemotherapy works better for people with metastatic colorectal cancer. About 390 adults worldwide will receive different combinations of these drugs to find the safest and most …

This study follows 1,200 people with psoriatic arthritis across 15 countries for two years to see how long they stay on different advanced treatments in real-world settings. It compares the drug risankizumab against other available therapies to understand which treatments patient…

This study is testing whether a new drug called ABBV-142 can help control Idiopathic Pulmonary Fibrosis (IPF), a serious disease that scars the lungs and makes breathing difficult. About 165 adults with IPF will be randomly assigned to receive either the new drug or a placebo for…

This study is testing a one-time gene therapy called RGX-314 for wet age-related macular degeneration (wet AMD), a leading cause of vision loss. It aims to help the eye make its own medicine to control leaky blood vessels, potentially reducing or eliminating the need for lifelong…

This study is testing whether an oral medication called upadacitinib can help control Crohn's disease in children aged 2 to 18 who haven't responded well to standard treatments. About 110 children worldwide will take the medication daily for up to 3 years while doctors monitor th…

This study is testing whether combining two investigational drugs works better than standard treatment for advanced non-small cell lung cancer. Researchers will enroll 252 adults who haven't received prior treatment for their advanced cancer to test safety, find the best dose, an…

This study is for women whose ovarian cancer has returned but responded well to a second round of platinum chemotherapy. It tests if adding a newer, targeted drug (mirvetuximab soravtansine) to a standard maintenance drug (bevacizumab) can keep the cancer controlled longer and pr…

This study is testing whether a daily pill called upadacitinib can help regrow hair in people with severe alopecia areata, an autoimmune condition that causes patchy or total hair loss. It will involve about 123 teenagers and adults in Japan who have lost at least 25% of their sc…

This study is testing whether a daily pill called ubrogepant can prevent migraines that occur around a woman's menstrual period. About 500 adult women with a history of menstrual migraines will take either the study pill or a placebo for 7 days each month. Researchers will track …

This early-stage study is testing a new drug called etentamig (ABBV-383) for adults with multiple myeloma that has returned or stopped responding to other treatments. The main goal is to find the safest and most effective dose and to closely monitor for side effects, including a …

This study is monitoring the safety and real-world effectiveness of atogepant, an already-approved oral medication for preventing migraines. It will follow 3,000 Korean adults with chronic or episodic migraines who are prescribed the drug by their doctors as part of their normal …

This study is testing a small gel stent implant to lower eye pressure in people with glaucoma that hasn't been controlled well enough by medications or previous surgeries. About 130 participants will have the stent placed using one of two different surgical approaches and will be…

This study is testing whether the drug venetoclax can help control chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) in adults whose cancer has come back or stopped responding to other treatments. It is specifically for people who have already tried certain o…

This study is testing a drug called risankizumab in children and teenagers (ages 2 to 18) with moderate to severe Crohn's disease who haven't responded well to other treatments. The goal is to see if the drug can safely reduce gut inflammation and control symptoms like abdominal …

This study is comparing the effectiveness and safety of the XEN45 implant against traditional glaucoma surgery (trabeculectomy) in Chinese patients with open-angle glaucoma. About 130 adults who haven't had success with standard eye pressure medications or laser treatments will r…

This study is testing a new, slow-release implant called AGN-193408 SR that is placed inside the eye. The goal is to see if it can safely and effectively lower eye pressure for people with open-angle glaucoma or ocular hypertension, potentially reducing the need for daily eye dro…

This study aims to see which of two existing drugs works better and is safer for controlling moderate to severe eczema in children aged 2 to 12. About 675 children worldwide will take either a daily pill (upadacitinib) or receive injections every few weeks (dupilumab) for up to t…

This study is testing whether an investigational drug called ABBV-CLS-628 can safely slow the progression of autosomal dominant polycystic kidney disease (ADPKD), a genetic condition where fluid-filled cysts damage the kidneys. About 240 adults with ADPKD will receive either the …

This study is testing a new drug called IMGN151, both by itself and combined with other cancer treatments, for women with certain gynecologic cancers like ovarian cancer. The main goals are to find safe doses and see if the treatments help control the cancer. About 377 participan…

This study is testing a new eye injection called ABBV-6628 for people with geographic atrophy, an advanced form of dry age-related macular degeneration that causes vision loss. The main goals are to check the safety of the injection and see how the body processes it. Researchers …

This study follows 700 adults with advanced lymphoma who are receiving epcoritamab treatment as prescribed by their doctors. Researchers will track how well the treatment works in real-world settings across 12-20 countries. Participants will be monitored for up to 3 years during …

This study tests whether a pill called upadacitinib can help adults with moderate-to-severe eczema who didn't get enough relief from their current injectable medication, dupilumab. About 200 participants worldwide will take either the pill or continue injections for 32 weeks to s…

This program provides eligible patients with small cell lung cancer access to the investigational drug ABBV-706 before it is officially approved. A doctor must determine if the potential benefit outweighs the risks for each individual patient. The program is not for patients who …

This study is testing an experimental drug called mirvetuximab soravtansine for women with advanced ovarian, fallopian tube, or primary peritoneal cancer that has stopped responding to platinum-based chemotherapy. The main goals are to find the best dosing schedule and to see how…

This study is testing a new drug, surzetoclax, to see if it is safe and can help control multiple myeloma that has come back or stopped responding to other treatments. It will enroll about 130 adults who have already tried several other therapies. The drug will be tested both by …

This study is testing whether a new oral medication called Icalcaprant can help control symptoms of major depression. About 195 adults currently experiencing a depressive episode will take either the drug or a placebo pill daily for six weeks. Researchers will measure changes in …

This study is testing whether giving the same drug combination again can help control chronic lymphocytic leukemia (CLL) when it returns after previous treatment. The trial will enroll 75 adults whose CLL came back more than a year after they finished their first treatment with v…

This study is testing a new drug called etentamig (ABBV-383) for adults with multiple myeloma, a blood cancer, that has returned or is not responding to current treatments. The main goals are to find a safe dose, see how the body processes the drug, and check for side effects. Ab…

This study is testing whether a new drug called Icalcaprant can help control depressive episodes in adults with bipolar I or II disorder. About 195 participants will take either the drug or a placebo pill daily for six weeks, while continuing their current mood stabilizer medicat…

This study aims to see how well an already-approved Parkinson's drug (ABBV-951) works over three years in real-world medical settings. It will follow 450 adults with advanced Parkinson's who are receiving the drug as part of their normal care. Researchers will track changes in da…

This study is testing whether an experimental drug called AGN-151607-DP can help surgeons close abdominal hernias without needing complex additional procedures. About 200 adults in the US with abdominal hernias needing open surgery will receive either the drug or a placebo inject…

This study is testing a new drug called etentamig, both alone and combined with other cancer medications, for people with multiple myeloma. It aims to find safe doses and see if these treatments can help control the cancer. About 440 adults with newly diagnosed or returning multi…

This study follows 200 adults with moderate to severe ulcerative colitis in Germany and Austria who are already prescribed the medication risankizumab by their doctors. Researchers will track how well the drug controls symptoms like bowel frequency and rectal bleeding over one ye…

This study is testing whether a new targeted drug called mirvetuximab soravtansine, when combined with standard chemotherapy (carboplatin), can shrink tumors before surgery in people with advanced ovarian, fallopian tube, or primary peritoneal cancer. The treatment is designed to…

This study is testing if a medication called cariprazine can help control the depressive episodes in teenagers (ages 10-17) who have bipolar I disorder. About 380 teens will be randomly assigned to receive either the study drug or a placebo for 6 weeks, followed by safety checks.…

This is the first study in people testing an experimental oral drug called ABBV-101 for adults with advanced B-cell blood cancers that have returned or not responded to prior treatments. The main goals are to find a safe dose and see how the body processes the drug, while also ch…

This study aims to understand the long-term safety and side effects of an experimental oral medication called ABBV-932 for adults with bipolar disorder who are experiencing a depressive episode. About 200 participants will take the drug for 26 weeks, followed by a safety check. T…

This study follows 270 Italian adults with advanced Parkinson's disease who are already prescribed the medication Foslevodopa/Foscarbidopa. Researchers will observe how the treatment affects patients' quality of life and daily activities over 12 months in a real-world setting, no…

This is the first study in people to test the safety and behavior of a new drug called azirkitug. It will be given alone and in combination with two other cancer drugs to adults with advanced solid tumors, including lung and head and neck cancers, who have already tried standard …

This study is testing a new combination of two drugs, etentamig and iberdomide, for adults whose multiple myeloma has come back or stopped responding to other treatments. The main goals are to find a safe and tolerable dose and to see if the combination can help control the disea…

This study is observing how well the drug venetoclax works for people with chronic lymphocytic leukemia (CLL) in real-world clinic settings. It will follow 500 patients in Austria, Germany, and Switzerland who are prescribed this medication, either alone or in combination with ot…

This is the first study in people testing an experimental oral drug called ABBV-525 for several types of advanced B-cell blood cancers, including lymphoma and leukemia. The main goals are to find a safe dose, see how the body processes the drug, and check for early signs that it …

This is the first human study testing an experimental drug called ABBV-901 for advanced ovarian cancer that has stopped responding to standard platinum-based chemotherapy. Researchers will enroll about 207 people to test the safety, side effects, and early signs of effectiveness …

This study is testing a new combination of drugs for adults with advanced stomach, gastroesophageal junction, or esophageal cancer that cannot be removed by surgery. Researchers want to find the safest and most effective dose of an experimental drug (telisotuzumab adizutecan) whe…

This study is testing a new oral drug called emraclidine for adults with schizophrenia. The main goals are to see if it is safe, how the body processes it, and if it helps reduce symptoms. About 268 participants will be randomly assigned to receive either the new drug or a placeb…

This study follows 400 adults in Germany, Austria, and Switzerland who are already prescribed upadacitinib (RINVOQ) by their doctor for moderate-to-severe ulcerative colitis. The goal is to see if patients who show improvement in their symptoms and gut inflammation after 8 weeks …

This study is comparing a new investigational drug called etentamig against standard available therapies for adults with multiple myeloma that has come back (relapsed) or stopped responding to treatment (refractory). Around 380 participants worldwide will be randomly assigned to …

This study is observing how well two already-approved medications work for people with moderate-to-severe Crohn's disease who did not get full relief from their first biologic treatment. It will follow 250 patients in Italy for up to 18 months as they take either upadacitinib or …

This is the first study in people to test a new drug called ABBV-319 for several types of blood cancer that have come back or stopped responding to other treatments. The main goals are to find a safe dose, see how the body processes the drug, and check for early signs that it mig…

This study aims to find the best way to protect patients' eyes from side effects caused by a targeted ovarian cancer drug called mirvetuximab soravtansine. It will enroll 100 women with recurrent ovarian cancer whose tumors have a specific marker. Participants will be randomly as…

This program provides early access to an investigational cancer drug called telisotuzumab adizutecan for people with solid tumors. It is for patients who have no other suitable treatment options and do not qualify for ongoing clinical trials. A doctor must determine if the potent…

This study aims to see if the medication risankizumab works better than vedolizumab for adults with moderate to severe ulcerative colitis who haven't tried similar advanced treatments. About 530 participants worldwide will be randomly assigned to receive one of the two approved d…

This study is testing an investigational drug called telisotuzumab adizutecan for people with a specific type of advanced lung cancer (EGFR-mutated non-squamous NSCLC) whose cancer has continued to grow despite treatment with a modern targeted therapy. The goal is to see if this …

This program provides eligible patients with non-small cell lung cancer access to an investigational drug called telisotuzumab vedotin before it receives full regulatory approval. It is designed for patients who have no other suitable treatment options and do not qualify for ongo…

This is the first human study of an experimental drug called ABBV-291 for adults with non-Hodgkin's lymphoma that has returned or not responded to at least two prior treatments. The main goals are to find a safe dose, see how the body processes the drug, and check for early signs…

This program provides early access to the investigational drug tavapadon for people with Parkinson's disease before it is officially approved. It is for eligible patients whose doctors determine the potential benefits outweigh the risks. The program is not for people who have oth…

This large, late-stage study is testing whether a daily pill called upadacitinib can help regrow hair in people with severe alopecia areata, an autoimmune condition that causes patchy or total hair loss. About 1500 participants, including teens and adults, will take either the ac…

This study aims to understand how people in China actually use the eczema medication upadacitinib in everyday practice, outside of strict clinical trials. It will follow about 1000 adolescents and adults with moderate-to-severe eczema for approximately 12 months. Researchers will…

This study is testing whether a new injectable medication called risankizumab is safe and effective for children with juvenile psoriatic arthritis, a condition causing painful, swollen joints. About 40 children worldwide will receive either risankizumab or an approved drug called…

This study compares how long patients with moderate to severe rheumatoid arthritis continue taking two different types of medications in real-world German clinics. Researchers will follow 678 patients for up to two years to see whether they stay on Upadacitinib or TNF-inhibitor t…

This early-stage study is testing a new drug called ABBV-319 in people with lupus or Sjogren's disease, two conditions where the immune system attacks the body. The main goals are to find a safe dose, see how the drug moves through the body, and check if it reduces the overactive…

This study aims to see how well the approved migraine prevention drug atogepant works for adults in real-world settings, outside of controlled clinical trials. It will follow about 1000 people who have been prescribed the drug by their doctors for two years. The main goal is to m…

This study is testing an experimental drug called etentamig (ABBV-383) for adults with AL amyloidosis, a rare disease where abnormal proteins damage organs. The trial aims to find a safe and effective dose and see if the drug can reduce disease markers in the blood and improve or…

This study is testing whether a new combination of two investigational drugs, livmoniplimab and budigalimab, plus standard chemotherapy works better and is safer than the current standard treatment (pembrolizumab plus chemotherapy) for people with advanced non-small cell lung can…

This study is testing whether a daily pill called atogepant can safely reduce how often children and teenagers get migraines. It will involve about 450 kids aged 6 to 17 who have frequent migraine attacks. For 12 weeks, participants will take either the study drug at a low or hig…

This study is testing an experimental injection called MEDI0618 to see if it safely reduces how often people get migraines. It will compare the drug against a placebo (a shot with no medicine) in about 488 adults who get episodic migraines. The main goal is to see if the treatmen…

This study is testing a combination of two drugs, venetoclax and azacitidine, for adults in India newly diagnosed with an aggressive blood cancer called acute myeloid leukemia (AML) who are not eligible for standard intensive chemotherapy. The main goals are to see how well the t…

This study follows 80 Chinese adults with moderate to severe ulcerative colitis who are already prescribed the drug upadacitinib by their doctor. The goal is to see how well the medication works in real-world use over one year. Researchers will collect routine health data from re…

This study is testing a medication called risankizumab in children and teenagers (ages 2 to 18) who have moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. The main goals are to find the right dose for children, see how well it controls the disease, and …

This study aims to see if switching from standard synthetic thyroid medication (T4) to a natural thyroid medication (Armour Thyroid) works just as well for controlling hypothyroidism. It will involve 2,800 adults who are already stable on their current T4 treatment. Researchers w…

This study is testing whether an experimental drug can prevent colorectal cancer from returning better than the current standard of care. It is for patients who have finished initial treatment and have no visible cancer on scans, but still have traces of cancer DNA in their blood…

This program provides early access to the drug venetoclax for patients with certain blood cancers like leukemia and lymphoma before it is fully approved in their country. It is for patients who have no other suitable treatment options and do not qualify for ongoing clinical trial…

This is a first-in-human study to test the safety and early effectiveness of a new oral drug called ABBV-711, given alone or in combination with another drug, for adults with advanced squamous tumors. The trial is for people with cancers like certain lung or head and neck cancers…

This study is testing a one-time gene therapy called RGX-314 for people with wet age-related macular degeneration (wet AMD), a leading cause of vision loss. The goal is to see if this single treatment can help control the disease long-term, potentially freeing patients from the b…

This study is testing an investigational drug called telisotuzumab adizutecan for people with advanced solid tumors that have a specific genetic feature called MET amplification. The main goals are to see how safe the drug is and whether it can shrink or control the tumors. About…

This study is testing whether the drug upadacitinib can help control moderate-to-severe hidradenitis suppurativa (HS), a painful inflammatory skin condition, in people who haven't responded well to previous biologic treatments. About 1,328 adult and adolescent participants worldw…

This study is observing how well the migraine medication ubrogepant helps patients return to normal daily activities and how satisfied they are with the treatment. About 167 adults in Canada who experience at least 3 moderate-to-severe migraine attacks per month will participate.…

This study aims to understand how different oral treatment schedules for chronic lymphocytic leukemia (CLL) affect patients' quality of life and daily functioning. Researchers will follow 132 adults in Spain who are already receiving standard oral treatments, either for newly dia…

This study is testing an investigational gel injection called ELAPR002f to see if it is safe and effective for improving the appearance of moderate to severe indented acne scars on the cheeks. About 395 adults will receive up to three injections over two months and be followed fo…

This study is testing a drug called eluxadoline to see if it is safe and can help children and teenagers (ages 6-17) who have irritable bowel syndrome with diarrhea (IBS-D). Researchers want to know if the medicine can improve stool consistency and reduce abdominal pain. The stud…

This study is testing a new injectable gel called NOA VOLUME to see if it is safe and works as well as an existing product (Juvéderm Voluma) for adding volume to the cheeks. About 231 adults with moderate to severe cheek volume loss will be randomly assigned to receive one of the…

This study is testing a new drug called ABBV-932 to see if it helps adults with generalized anxiety disorder (GAD) who still feel very anxious despite taking standard antidepressant medication. About 315 participants will be randomly assigned to take either the new drug or a plac…

This study aims to see if a new artificial tear formula, ABBV-444, works better and is as safe as a widely used brand, Refresh Optive, for people with dry eye disease. About 250 adults with moderate to severe dry eye symptoms will use one of the two eye drops for 90 days. Researc…

This study is testing if taking the migraine medication ubrogepant during the early 'prodrome' phase—when people first notice warning signs like fatigue or light sensitivity—can prevent moderate or severe headaches from developing over the next 24 hours. It involves about 189 adu…

This study is testing if a pill called ubrogepant is safe and effective at quickly stopping migraine attacks in children and teenagers aged 6 to 17. Ubrogepant is already approved for adults. About 1,059 young people with a history of migraines will take either the study drug or …

This study is testing if a pill called atogepant can quickly stop migraine attacks when taken at the start of symptoms. It will involve about 1300 adults with a history of migraines. Participants will try the pill or a placebo for four migraines, then all receive the active pill,…

This study is observing whether an already-approved Parkinson's medication (Foslevodopa/Foscarbidopa) helps improve sleep problems in people with advanced Parkinson's disease. About 103 adults in Spain who are already prescribed this medication by their doctor will be followed fo…

This is the very first study testing a new experimental drug called ABBV-1042 in people. Researchers will give increasing single doses of the oral drug to 48 healthy volunteers to check for side effects and see how the body processes it. The main goal is to determine if the drug …

This is the first study testing the experimental drug ABBV-277 in humans. Researchers will give single doses to 40 healthy volunteers to check for safety and see how the body processes the drug. The main goal is to understand side effects and how long the drug stays in the bloods…

This study aims to understand how three skin conditions—alopecia areata (hair loss), vitiligo (skin depigmentation), and hidradenitis suppurativa (painful skin lumps)—affect people's daily lives and quality of life. It will survey nearly 2,800 adolescents and adults with moderate…

This is the first study in humans to test the safety of an experimental drug called ABBV-243. It will involve 66 healthy adult volunteers to see how their bodies process the drug and what side effects might occur. The study will test different doses given by injection and will in…

This study aims to understand how doctors around the world use a specific treatment strategy for Crohn's Disease and Ulcerative Colitis, and whether using this strategy leads to better results for patients. It will look back at the medical records of 2,000 adults who have had the…

This study aims to understand the safety of two migraine medicines, Ubrelvy and Qulipta, when taken during pregnancy. It will follow about 1,884 pregnant women with migraines in the US and Canada to track health outcomes for both mothers and their babies up to one year after birt…

This early-stage study aims to understand how the body absorbs and processes a new drug called ABBV-8736. It will compare giving the drug as a simple shot under the skin versus through an IV drip. The study involves 40 healthy adult volunteers to check how the drug moves through …

This is a very early study to see how a new drug called emraclidine moves through the body and how safe it is for healthy older adults to take. Researchers will give the drug to a small group of 32 elderly volunteers and closely monitor them for any side effects. The main goal is…

This early-stage study aims to understand how a new injectable drug called ABBV-295 interacts with common birth control pills. It will involve 20 healthy adult women who have overweight or obesity. The main goal is to check for safety issues and see how the body processes these d…

This is the first study testing a new drug called ABBV-547 in people. Researchers will give single doses to 87 healthy adults to check for side effects and see how the body processes the drug. The main goal is to understand the drug's safety before testing it in people with medic…