Abbvie

This study tested whether adding two drugs, venetoclax and azacitidine, as ongoing 'maintenance therapy' could help people with acute myeloid leukemia (AML) live longer after a stem cell transplant. It compared this drug combination to standard supportive care alone. The goal was…

This was an early safety study for a new cancer drug called ABBV-303, tested alone and in combination with another drug, budigalimab. It involved adults with advanced solid tumors that had stopped responding to other treatments. The main goal was to find a safe dose and see how t…

This study aimed to test the safety and effectiveness of a liquid medicine called paricalcitol for treating a serious hormone imbalance in children aged 0 to 9 with end-stage kidney disease who are on dialysis. The goal was to see if the medicine could safely lower high hormone l…

This study tested whether BOTOX injections could prevent migraine attacks in adults who get frequent episodic migraines. About 775 participants worldwide received either BOTOX or a placebo injection into their head and neck muscles every 12 weeks. The main goal was to see if BOTO…

This early-stage study tested a new oral medication called fosigotifator for treating major depressive disorder (MDD). It aimed to see if the drug was safe and effective for adults with depression. The study was terminated early and only involved a small group of participants.

This study aimed to check the long-term safety of an experimental add-on medication called CVL-865 for adults whose focal seizures are not fully controlled by their current drugs. It was a follow-up study for 105 people who had already completed a previous short-term trial. The m…

This study tested an experimental drug called telisotuzumab vedotin for adults with advanced non-small cell lung cancer that has a specific genetic feature called MET amplification. The goal was to see if the drug could shrink tumors and control the cancer. The trial was terminat…

This study tested how safe and effective the medication cariprazine is for treating adults with schizophrenia in Japan and Taiwan. The trial was designed to last 6 months but was stopped early after enrolling only 34 participants. Researchers compared the drug against a placebo t…

This study tested whether two experimental drugs could help control HIV when people temporarily stopped their regular antiretroviral therapy. About 160 adults with well-controlled HIV participated, receiving either the study drugs or placebo while closely monitored during their t…

This study tested an experimental drug called CVL-871 to see if it was safe and could help reduce apathy—a lack of motivation and emotional response—in people with dementia. It involved 41 participants with mild to moderate dementia and significant apathy. The trial was terminate…

This study aims to understand the safety of the medications Orilissa and Oriahnn (which contain elagolix) during pregnancy. Researchers are following pregnant women who have taken these drugs for conditions like endometriosis or fibroids, comparing their pregnancy outcomes to wom…

This early-stage study aimed to check the safety of a new drug called ABBV-1088 and see how the body absorbs and processes it. It involved 72 healthy adults from Western, Chinese, and Japanese backgrounds. The study also looked at how the drug might interact with another common m…