Abbvie

This study tested an oral medication, NX-13, in 81 adults with moderate to severe ulcerative colitis. Participants received either NX-13 or a placebo for 12 weeks, with a long-term follow-up option. The trial was terminated early, so the full results are not available, but the da…

This study tested a liquid medicine called paricalcitol in children aged 0 to 9 years with severe kidney failure who are on dialysis. The goal was to see if it safely lowers high parathyroid hormone levels, a common complication. The trial was stopped early after enrolling only 2…

This study tested whether adding venetoclax and azacitidine after a stem cell transplant could help people with acute myeloid leukemia (AML) live longer. It included adults and teens who had recently received a transplant. The trial was stopped early, so the full benefits and ris…

This study tested an experimental drug called cofetuzumab pelidotin for people with a specific type of advanced lung cancer (non-small cell lung cancer) that had returned after other treatments. The drug was designed to target a protein called PTK7 found on cancer cells. The stud…

This study looked at the long-term safety of an experimental drug called CVL-865 in adults whose focal seizures were not controlled by other medications. About 105 people who completed a previous trial took CVL-865 alongside their usual seizure drugs for up to 57 weeks. The study…

This early-phase study tested an experimental drug called ABBV-303, alone or with another drug (budigalimab), in adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. The study was termin…

This study tested two experimental drugs, budigalimab and ABBV-382, in people with HIV who were stable on standard therapy. Participants stopped their usual HIV medications to see if the new drugs could keep the virus under control. The trial was terminated early, so it's unclear…

This study tested an experimental drug called telisotuzumab vedotin for people with a specific type of advanced lung cancer (non-squamous non-small cell lung cancer) that has a MET gene change. The goal was to see if the drug could shrink tumors. The trial was stopped early and e…

This study tested cariprazine (VRAYLAR), an approved schizophrenia drug in the U.S., for people with acute schizophrenia in Japan and Taiwan. Participants received either cariprazine or a placebo for 6 weeks, then could continue on cariprazine for 18 more weeks. The trial was ter…

This study tested whether BOTOX injections can prevent migraine attacks in adults who have 6 to 14 migraine days per month (episodic migraine). About 775 participants received either BOTOX or placebo injections into their muscles twice, 12 weeks apart. The main goal was to see if…

This phase 2 trial tested whether darigabat, an oral tablet, could help people with panic disorder. About 80 participants took either darigabat or a placebo for several weeks. The goal was to see if the drug could reduce panic attacks and improve overall symptoms. The study was t…

This study tested a drug called CVL-871 to see if it is safe and can help reduce apathy (lack of motivation or interest) in people with dementia. The trial included 41 participants with mild to moderate dementia and clinically significant apathy. The main goal was to check for si…

This study tested a new medicine called fosigotifator for adults with major depressive disorder. The goal was to see if it is safe and helps with depression symptoms. About 20 people were enrolled before the study was stopped early. Participants took either the drug or a placebo,…

This was a Phase 1 study to check the safety and how the body processes ABBV-1088 in healthy adults, including Western, Han-Chinese, and Japanese participants. It also looked at how ABBV-1088 interacts with another drug, itraconazole. The study was terminated early, so no results…

This registry aimed to track pregnancy outcomes in women who were exposed to elagolix (brand names Orilissa and Oriahnn) for endometriosis or uterine fibroids. The study planned to enroll 584 pregnant women, half with elagolix exposure and half without, and follow them through pr…