Abbvie

This early-stage trial tests a drug called pivekimab sunirine in about 18 children whose acute myeloid leukemia (AML) has come back or not responded to standard treatments. The main goals are to check safety and how the drug moves through the body. Participants receive the drug b…

This study tests a new drug, telisotuzumab adizutecan, combined with bevacizumab, against the standard treatment (LONSURF plus bevacizumab) in about 700 adults with advanced colorectal cancer that has stopped responding to prior therapies. The goal is to see if the new combinatio…

This study tests a new drug, ABBV-706, against standard treatments for small cell lung cancer that has returned or not responded to therapy. About 531 adults will receive either ABBV-706 or usual care (topotecan, lurbinectedin, or amrubicin) to see which works better. The goal is…

This study tests a new drug, telisotuzumab adizutecan, combined with standard chemotherapy (FOLFOX) in people with metastatic pancreatic cancer that has spread. About 900 adults will receive either the new combination or standard care. The goal is to see if the new treatment shri…

This study looks at how well an approved Parkinson's drug, Foslevodopa/Foscarbidopa, works in people with earlier advanced Parkinson's disease. About 100 adults will receive the drug as a continuous infusion under the skin for up to 6 months. The goal is to see if it reduces 'off…

This study looks at tissue samples from 200 people with relapsed ovarian, fallopian tube, or primary peritoneal cancer. Researchers want to see how often a protein called folate receptor alpha is found at high levels on tumor cells. No new treatments are given—the goal is simply …

This early-stage study tests a new drug called ABBV-1451 in healthy volunteers to see how safe it is and how the body processes it. About 90 adults, including Japanese and Han Chinese participants, will receive a single dose. The goal is to gather initial safety and drug-level in…

This study looks at how well different labs agree when testing for a protein called FRa in stored tissue samples from people with ovarian cancer. About 1,000 women will have their old biopsy samples tested again. No new treatments or visits are needed. The goal is to improve futu…

This study tests how the drug risankizumab behaves in the body when given as a shot under the skin versus through a vein. It involves 60 healthy adults and aims to measure drug levels and any side effects. The results will help guide future dosing for patients with conditions lik…