Abbvie

This phase 3 trial is testing whether an investigational drug called ABBV-1480, when combined with chemotherapy, works better than the current standard treatment (pembrolizumab plus chemotherapy) for adults with advanced or metastatic squamous non-small cell lung cancer. Particip…

This phase 2 trial is testing whether adding an investigational drug called telisotuzumab adizutecan to the standard immunotherapy pembrolizumab can better control recurrent or metastatic head and neck squamous cell carcinoma. The study enrolls adults whose tumors express a speci…

This clinical trial is testing an experimental drug called ABBV-295 to see if it can help adults with obesity or overweight lose weight. The study will compare different doses of the drug against a placebo (a dummy injection) to measure its effect on body weight over 32 weeks. Pa…

This study looks at how well upadacitinib, a daily pill, works compared to biologic injections for people with moderate-to-severe atopic dermatitis (eczema). The goal is to see if more patients can reach a state of minimal disease activity, meaning nearly clear skin and little to…

This phase 3 trial is testing whether an experimental drug called etentamig, combined with pomalidomide, can control multiple myeloma that has come back or stopped responding to treatment. About 520 adults who have already tried 1 to 3 prior therapies will be randomly assigned to…

This study tests whether combining risankizumab with either trosunilimab or ABBV-701 can safely reduce inflammation and improve symptoms in adults with moderately to severely active Crohn's disease or ulcerative colitis. Participants are randomly assigned to one of the combinatio…

This study looks at how well atogepant, a daily pill, works to prevent migraines in adults treated in UK primary care. About 200 people with migraine will take atogepant as prescribed by their doctor and report their symptoms and healthcare use for up to 48 weeks. The goal is to …

This study monitors the safety and effectiveness of mirvetuximab soravtansine (MIRV) in people with a specific type of ovarian, fallopian tube, or primary peritoneal cancer that has stopped responding to platinum-based chemotherapy and tests positive for the folate receptor-alpha…

This study looks at how well the drug Foslevodopa/Foscarbidopa works for people with advanced Parkinson's disease who are still in the earlier phases of that stage. About 100 adults will receive the drug as a continuous infusion under the skin for up to 6 months. Researchers will…

This early-stage trial is testing whether giving two different botulinum toxin injections in sequence can safely and effectively reduce moderate-to-severe frown lines between the eyebrows. About 120 healthy adults will receive an investigational drug called AGN-151586, followed b…

This trial tests an experimental injection called AGN-151586 for adults with moderate to severe forehead lines. The goal is to see if the treatment is safe and can reduce the appearance of these wrinkles. Participants receive the injection and are monitored for side effects and c…

This early-stage study looks at how a new drug called ABBV-932 moves through the body when taken with another drug, itraconazole. Twenty healthy adults will take both drugs and have their blood levels measured. The goal is to check for side effects and see if itraconazole changes…

This study will use artificial intelligence (AI) to analyze eye scans from 554 adults with diabetic macular edema (DME). The goal is to see if AI can predict when a person's eye treatment needs to change. Participants will not receive any new treatment; instead, researchers will …