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Seizure drug study ends early – safety results awaited

NCT ID NCT04686786

Terminated Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at the long-term safety of an experimental drug called CVL-865 in adults whose focal seizures were not controlled by other medications. About 105 people who completed a previous trial took CVL-865 alongside their usual seizure drugs for up to 57 weeks. The study was stopped early, and researchers tracked side effects, heart changes, and withdrawal symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

epilepsy focal epilepsy visual epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEIZURES

Contacts and locations

Locations

  • Baltimore, Maryland

    Baltimore, Maryland, 21287, United States

  • Barcelona, Catalonia

    Barcelona, Catalonia, 08035, Spain

  • Barcelona, Catalunya

    Barcelona, Catalonia, 08003, Spain

  • Bethesda, Maryland

    Bethesda, Maryland, 20817, United States

  • Białystok

    Bialystok, 15-704, Poland

  • Boston, Massachusetts

    Boston, Massachusetts, 02114, United States

  • Bydgoszcz, Kujawsko-Pomorskie

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-163, Poland

  • Camperdown, New South Wales

    Camperdown, New South Wales, 2050, Australia

  • Charleston, South Carolina

    Charleston, South Carolina, 29425, United States

  • Chesterfield, Missouri

    Chesterfield, Missouri, 63005, United States

  • Fitzroy, Victoria

    Fitzroy, Victoria, 3065, Australia

  • Gdańsk, Pomorskie

    Gdansk, Pomeranian Voivodeship, 80-803, Poland

  • Gulf Breeze, Florida

    Gulf Breeze, Florida, 32561-4458, United States

  • Gwangjin-gu, Seoul

    Gwangju, Seoul, 05030, South Korea

  • Hackensack, New Jersey

    Hackensack, New Jersey, 07601, United States

  • Heidelberg, Victoria

    Heidelberg, Victoria, 3084, Australia

  • Herston, Queensland

    Herston, Queensland, 4029, Australia

  • Honolulu, Hawaii

    Honolulu, Hawaii, 96817, United States

  • Irwon-Ro Gangnam-gu., Seoul

    Irwon-dong, Seoul, 06351, South Korea

  • Jacksonville, Florida

    Jacksonville, Florida, 32224, United States

  • Kragujevac, Sumadija

    Kragujevac, Sumadija, 34000, Serbia

  • Kraków, Malopolskie

    Krakow, Lesser Poland Voivodeship, 31-209, Poland

  • Kyiv

    Kyiv, 02091, Ukraine

  • Lexington, Kentucky

    Lexington, Kentucky, 40504, United States

  • Little Rock, Arkansas

    Little Rock, Arkansas, 72205, United States

  • Lodz

    Lodz, Łódź Voivodeship, 90-752, Poland

  • Lviv

    Lviv, 79035, Ukraine

  • Madrid

    Madrid, 28034, Spain

  • Madrid

    Madrid, 28040, Spain

  • Malaga,

    Málaga, Andalusia, 29010, Spain

  • Melbourne, Victoria

    Melbourne, Victoria, 3004, Australia

  • Miami Lakes, Florida

    Miami Lakes, Florida, 33016, United States

  • Nashville, Tennessee

    Nashville, Tennessee, 37232, United States

  • Neurology Department, Kragujevac

    Kragujevac, Sumadija, 34000, Serbia

  • New Haven, Connecticut

    New Haven, Connecticut, 06519, United States

  • New York

    New York, New York, 10021, United States

  • Oklahoma City, Oklahoma

    Oklahoma City, Oklahoma, 73112, United States

  • Orlando, Florida

    Orlando, Florida, 32806, United States

  • Parkville, Victoria

    Parkville, Victoria, 3050, Australia

  • Philadelphia, Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Philadelphia, Pennsylvania

    Philadelphia, Pennsylvania, 19107, United States

  • Port Charlotte, Florida

    Port Charlotte, Florida, 33952, United States

  • Randwick, New South Wales

    Randwick, New South Wales, 2031, Australia

  • Rochester, New York

    Rochester, New York, 14642, United States

  • Saint Louis, Missouri

    St Louis, Missouri, 63110, United States

  • Salt Lake City, Utah

    Salt Lake City, Utah, 84132, United States

  • Scarborough, Maine

    Scarborough, Maine, 04074, United States

  • Sevilla

    Seville, 41013, Spain

  • Tampa, Florida

    Tampa, Florida, 33606, United States

  • Terrassa, Catalonia

    Terrassa, Catalonia, 08222, Spain

  • Toledo, Ohio

    Toledo, Ohio, 43614, United States

  • Uzhgorod

    Uzhhorod, Uzhgorod, 88018, Ukraine

  • Valencia

    Valencia, 46026, Spain

  • Warszawa

    Warsaw, 02-952, Poland

  • Westmead, New South Wales

    Westmead, New South Wales, 2145, Australia

  • Wojnicz, Lskie

    Wojnicz, Wojnicz Lskie, 40-650, Poland

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